0B68 Benovic, Jeffrey L. - Thomas Jefferson University - Thomas Jefferson University
jlb104

Jeffrey L. Benovic, PhD

Contact Dr. Benovic

233 S. 10th Street
Philadelphia, PA 19107

(215) 503-4607
(215) 503-5393 fax

Most Recent Peer-reviewed Publications

  1. Role of β-arrestins and arrestin domain-containing proteins in G protein-coupled receptor trafficking
  2. Caspase-cleaved arrestin-2 and BID cooperatively facilitate cytochrome C release and cell death
  3. Editorial overview: Cell regulation: The ins and outs of G protein-coupled receptors
  4. β-Arrestins and G protein-coupled receptor trafficking
  5. Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein
  6. G protein-coupled receptor kinase 2 (GRK2) is localized to centrosomes and mediates epidermal growth factor-promoted centrosomal separation
  7. β-Arrestins and G protein-coupled receptor trafficking
  8. Identification of phosphorylation sites in the COOH-terminal tail of the μ-opioid receptor
  9. G-protein-coupled receptors signal victory
  10. Identification and characterization of distinct c-terminal domains of the human hydroxycarboxylic acid receptor-2 that are essential for receptor export, constitutive activity, desensitization, and internalization
  11. G protein-coupled receptor kinase 5 phosphorylates nucleophosmin and regulates cell sensitivity to polo-like kinase 1 inhibition
  12. Structural domains required for Caenorhabditis elegans G protein-coupled receptor kinase 2 (GRK-2) function in Vivo
  13. G protein-coupled receptor kinase 5 is localized to centrosomes and regulates cell cycle progression
  14. Suppression of G-protein-coupled receptor kinase 3 expression is a feature of classical GBM that is required for maximal growth
  15. Differential expression of arrestins is a predictor of breast cancer progression and survival
  16. Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder
  17. G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4
  18. Bombyx adipokinetic hormone receptor activates extracellular signal-regulated kinase 1 and 2 via G protein-dependent PKA and PKC but β-arrestin-independent pathways
  19. Identification of the Rac-GEF P-Rex1 as an Essential Mediator of ErbB Signaling in Breast Cancer
  20. Internalization of the human nicotinic acid receptor GPR109A is regulated by Gi, GRK2, and arrestin3
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