Jeffrey L. Benovic, PhD

Contact Dr. Benovic

233 S. 10th Street
Philadelphia, PA 19107

(215) 503-4607
(215) 503-5393 fax

Most Recent Peer-reviewed Publications

  1. G protein-coupled receptor kinase 3 and protein kinase C phosphorylate the distal C-terminal tail of the chemokine receptor CXCR4 and mediate recruitment of β-arrestin
  2. Dysregulated GPCR signaling and therapeutic options in uveal melanoma
  3. Structural and Functional Analysis of a β2-Adrenergic Receptor Complex with GRK5
  4. G protein-coupled receptor kinase-2 (GRK-2) regulates serotonin metabolism through the monoamine oxidase AMX-2 in Caenorhabditis elegans
  5. G protein-coupled receptor kinases: Past, present and future
  6. β-arrestin-biased signaling through the β2-adrenergic receptor promotes cardiomyocyte contraction
  7. The αarrestin ARRDC3 regulates the endosomal residence time and intracellular signaling of the β2-adrenergic receptor
  8. From biased signalling to polypharmacology: Unlocking unique intracellular signalling using pepducins
  9. Interdicting Gq activation in airway disease by receptor-dependent and receptor-independent mechanisms
  10. Atomic structure of GRK5 reveals distinct structural features novel for G protein-coupled receptor kinases
  11. Structural biology: Arresting developments in receptor signalling
  12. New frontiers in kinases
  13. Herpes simplex virus enhances chemokine function through modulation of receptor trafficking and oligomerization
  14. Consequence of the tumor-associated conversion to cyclin D1b
  15. Development and characterization of pepducins as Gs-biased allosteric agonists
  16. Role of β-arrestins and arrestin domain-containing proteins in G protein-coupled receptor trafficking
  17. Call for papers! a special thematic compilation/special issue crossover with ACS chemical biology, ACS medicinal chemistry letters, and the journal of medicinal chemistry focused on new frontiers in kinases
  18. Editorial overview: Cell regulation: The ins and outs of G protein-coupled receptors
  19. β-Arrestins and G protein-coupled receptor trafficking
  20. β-Arrestins and G protein-coupled receptor trafficking