291E Cingolani, Gino - Thomas Jefferson University - Thomas Jefferson University
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Gino Cingolani, PhD

Contact Dr. Cingolani

233 S. 10th Street
826 BLSB
Philadelphia, PA 19107

(215) 503-4573
(215) 923-2117 fax

Most Recent Peer-reviewed Publications

  1. Divergent evolution of nuclear localization signal sequences in herpesvirus terminase subunits
  2. Structural plasticity of the protein plug that traps newly packaged genomes in podoviridae virions
  3. PARP-2 domain requirements for DNA damage-dependent activation and localization to sites of DNA damage
  4. A greasy aid to capsid assembly: Lessons from a salty virus
  5. Structure-based screen identifies a potent small molecule inhibitor of Stat5a/b with therapeutic potential for prostate cancer and chronic myeloid leukemia
  6. IPO3-mediated nonclassical nuclear import of NF-κB essential modulator (NEMO) drives DNA damage-dependent NF-κB activation
  7. Architecture of the Complex Formed by Large and Small Terminase Subunits from Bacteriophage P22
  8. Dimeric quaternary structure of human laforin
  9. Diversification of importin-α isoforms in cellular trafficking and
  10. Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2
  11. Molecular determinants for nuclear import of influenza A PB2 by importin α isoforms 3 and 7
  12. The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD
  13. Conservation of inner nuclear membrane targeting sequences in mammalian Pom121 and yeast Heh2 membrane proteins
  14. Structure of human PIR1, an atypical dual-specificity phosphatase
  15. Jamming up the "β-staple": Regulation of SIRT1 activity by its C-terminal regulatory segment (CTR)
  16. Exploring the atomic structure and conformational flexibility of a 320 Å long engineered viral fiber using X-ray crystallography
  17. Architecture of viral genome-delivery molecular machines
  18. Coordination of the filament stabilizing versus destabilizing activities of cofilin through its secondary binding site on actin
  19. The p53-induced factor Ei24 inhibits nuclear import through an importin β-binding-like domain
  20. Structural basis of allosteric interactions among Ca2+ -binding sites in a K+ channel RCK domain
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