27EC Cingolani, Gino - Thomas Jefferson University - Thomas Jefferson University

Gino Cingolani, PhD

Contact Dr. Cingolani

233 S. 10th Street
826 BLSB
Philadelphia, PA 19107

(215) 503-4573
(215) 923-2117 fax

Most Recent Peer-reviewed Publications

  1. A greasy aid to capsid assembly: Lessons from a salty virus
  2. Structure-based screen identifies a potent small molecule inhibitor of Stat5a/b with therapeutic potential for prostate cancer and chronic myeloid leukemia
  3. IPO3-mediated nonclassical nuclear import of NF-κB essential modulator (NEMO) drives DNA damage-dependent NF-κB activation
  4. Architecture of the Complex Formed by Large and Small Terminase Subunits from Bacteriophage P22
  5. Dimeric quaternary structure of human laforin
  6. Diversification of importin-α isoforms in cellular trafficking and
  7. Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2
  8. Molecular determinants for nuclear import of influenza A PB2 by importin α isoforms 3 and 7
  9. The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD
  10. Conservation of inner nuclear membrane targeting sequences in mammalian Pom121 and yeast Heh2 membrane proteins
  11. Structure of human PIR1, an atypical dual-specificity phosphatase
  12. Jamming up the "β-staple": Regulation of SIRT1 activity by its C-terminal regulatory segment (CTR)
  13. Exploring the atomic structure and conformational flexibility of a 320 Å long engineered viral fiber using X-ray crystallography
  14. Coordination of the filament stabilizing versus destabilizing activities of cofilin through its secondary binding site on actin
  15. The p53-induced factor Ei24 inhibits nuclear import through an importin β-binding-like domain
  16. Architecture of viral genome-delivery molecular machines
  17. Structural basis of allosteric interactions among Ca2+-binding sites in a K+ channel RCK domain.
  18. The Tip of the Tail Needle Affects the Rate of DNA Delivery by Bacteriophage P22
  19. Atomic structure of dual-specificity phosphatase 26, a novel p53 phosphatase
  20. Crystal structure of a Ba2+-bound gating ring reveals elementary steps in RCK domain activation