gxc012

Gino Cingolani, PhD

Contact Dr. Cingolani

233 S. 10th Street
826 BLSB
Philadelphia, PA 19107

(215) 503-4573
(215) 923-2117 fax

Most Recent Peer-reviewed Publications

  1. Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation
  2. Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death
  3. Divergent evolution of nuclear localization signal sequences in herpesvirus terminase subunits
  4. Structural plasticity of the protein plug that traps newly packaged genomes in podoviridae virions
  5. PARP-2 domain requirements for DNA damage-dependent activation and localization to sites of DNA damage
  6. Architecture of the Complex Formed by Large and Small Terminase Subunits from Bacteriophage P22
  7. A greasy aid to capsid assembly: Lessons from a salty virus
  8. Conservation of inner nuclear membrane targeting sequences in mammalian Pom121 and yeast Heh2 membrane proteins
  9. The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD
  10. Structure-based screen identifies a potent small molecule inhibitor of Stat5a/b with therapeutic potential for prostate cancer and chronic myeloid leukemia
  11. IPO3-mediated nonclassical nuclear import of NF-κB essential modulator (NEMO) drives DNA damage-dependent NF-κB activation
  12. Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2
  13. Dimeric quaternary structure of human laforin
  14. Diversification of importin-α isoforms in cellular trafficking and
  15. Molecular determinants for nuclear import of influenza A PB2 by importin α isoforms 3 and 7
  16. Structure of human PIR1, an atypical dual-specificity phosphatase
  17. Jamming up the "β-staple": Regulation of SIRT1 activity by its C-terminal regulatory segment (CTR)
  18. Exploring the atomic structure and conformational flexibility of a 320 Å long engineered viral fiber using X-ray crystallography
  19. Architecture of viral genome-delivery molecular machines
  20. The p53-induced factor Ei24 inhibits nuclear import through an importin β-binding-like domain