0B68 Fernandes-Alnemri, Teresa - Thomas Jefferson University - Thomas Jefferson University
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Teresa Fernandes-Alnemri, PhD

Contact Dr. Fernandes-Alnemri

233 S. 10th Street
902 BLSB
Philadelphia, PA 19107

(215) 503-4631

Most Recent Peer-reviewed Publications

  1. Cutting edge: TLR signaling licenses IRAK1 for rapid activation of the NLRP3 inflammasome
  2. The mitochondrial antiviral protein MAVS associates with NLRP3 and regulates its inflammasome activity
  3. Restoration of ASC expression sensitizes colorectal cancer cells to genotoxic stress-induced caspase-independent cell death
  4. Ribotoxic stress through p38 mitogen-activated protein kinase activates in Vitro the human pyrin inflammasome
  5. A novel role for the mitochondrial HTRA2/OMI protease in aging
  6. Loss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature aging
  7. Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation
  8. Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection
  9. Cutting edge: Mutation of Francisella tularensis mviN leads to increased macrophag 1218 e absent in melanoma 2 inflammasome activation and a loss of virulence
  10. Involvement of the AIM2, NLRC4, and NLRP3 inflammasomes in caspase-1 activation by Listeria monocytogenes
  11. The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
  12. Functional consequences of a germline mutation in the leucine-rich repeat domain of NLRP3 Identified in an atypical autoinflammatory disorder
  13. Anti-inflammatory compounds parthenolide and bay 11-7082 are direct inhibitors of the inflammasome
  14. Cutting edge: NF-κB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
  15. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
  16. Chapter Thirteen Assembly, Purification, and Assay of the Activity of the ASC Pyroptosome
  17. The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila
  18. Mutations in NALP12 cause hereditary periodic fever syndromes
  19. Pyrin Activates the ASC Pyroptosome in Response to Engagement by Autoinflammatory PSTPIP1 Mutants
  20. The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
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