Howard Gamper, Jr., PhD

Contact Dr. Gamper, Jr.

233 S. 10th Street
Philadelphia, PA 19107

(215) 503-9798
(215) 503-4954 fax

Most Recent Peer-reviewed Publications

  1. A novel HSD17B10 mutation impairing the activities of the mitochondrial Rnase P complex causes X-linked intractable epilepsy and neurodevelopmental regression
  2. The UGG isoacceptor of tRNAPro is naturally prone to frameshifts
  3. Maintenance of protein synthesis reading frame by EF-P and m 1 G37-tRNA
  4. Loss-of-function alanyl-tRNA synthetase mutations cause an autosomal-recessive early-onset epileptic encephalopathy with persistent myelination defect
  5. Post-transcriptional modifications to tRNA - A response to the genetic code degeneracy
  6. A Divalent Metal Ion-Dependent N1-Methyl Transfer to G37-tRNA
  7. Amino acid - Dependent stability of the acyl linkage in aminoacyl-tRNA
  8. The selective tRNA aminoacylation mechanism based on a single G.U pair
  9. Structural and mechanistic basis for enhanced translational efficiency by 2-thiouridine at the tRNA anticodon wobble position
  10. The temperature sensitivity of a mutation in the essential tRNA modification enzyme tRNA methyltransferase D (TrmD)
  11. Conservation of structure and mechanism by Trm5 enzymes
  12. Potential for interdependent development of tRNA determinants for aminoacylation and ribosome decoding.
  13. Distinct kinetic determinants for the stepwise CCA addition to tRNA
  14. RecA-mediated strand invasion of DNA by oligonucleotides substituted with 2-aminoadenine and 2-thiothymine
  15. Properties of pseudo-complementary DNA substituted with weakly pairing analogs of guanine or cytosine
  16. Pyrrolo-C as a molecular probe for monitoring conformations of the tRNA 3′ end
  17. tRNA Integrity Is a Prerequisite for Rapid CCA Addition: Implication for Quality Control
  18. Enzymatic synthesis of structure-free DNA with pseudo-complementary properties
  19. Fluorescent labeling of tRNAs for dynamics experiments
  20. Kinetic Quality Control of Anticodon Recognition by a Eukaryotic Aminoacyl-tRNA Synthetase