0B68 Keen, James H. - Thomas Jefferson University - Thomas Jefferson University

James H. Keen, PhD

Contact Dr. Keen

233 S. 10th Street
915 BLSB
Philadelphia, PA 19107

(215) 503-4624
(215) 503-0622 fax

Most Recent Peer-reviewed Publications

  1. Clathrin light chains are required for the gyrating-clathrin recycling pathway and thereby promote cell migration
  2. Arf6 regulation of Gyrating-Clathrin
  3. GGA3 functions as a switch to promote met receptor recycling, essential for sustained ERK and cell migration
  4. Development and application of in vivo molecular traps reveals that dynein light chain occupancy differentially affects dynein-mediated processes
  5. Gyrating clathrin: Highly dynamic clathrin structures involved in rapid receptor recycling
  6. Interaction of prostate specific membrane antigen with clathrin and the adaptor protein complex-2
  7. Phosphoinositide 3-kinase C2α links clathrin to microtubule-dependent movement
  8. Dynamics of membrane clathrin-coated structures during cytokinesis
  9. Individual phosphoinositide 3-kinase C2α domain activities independently regulate clathrin function
  10. Membrane targeting of endocytic adaptors: Cargo and lipid do it together
  11. Major histocompatibility complex class I-intercellular adhesion molecule-1 association on the surface of target cells: Implications for antigen presentation to cytotoxic T lymphocytes
  12. The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4
  13. A glimpse of coated vesicle creation? Well almost!
  14. G protein-coupled receptor/arrestin3 modulation of the endocytic machinery
  15. The actin-binding protein Hip1R associates with clathrin during early stages of endocytosis and promotes clathrin assembly in vitro
  16. The class II phosphoinositide 3-kinase C2α is activated by clathrin and regulates clathrin-mediated membrane trafficking
  17. Selective recruitment of arrestin-3 to clathrin coated pits upon stimulation of G protein-coupled receptors
  18. The class II phosphoinositide 3-kinase PI3K-C2α is concentrated in the trans-Golgi network and present in clathrin-coated vesicles
  19. Phosphoinositide-AP-2 interactions required for targeting to plasma membrane clathrin-coated pits
  20. Acute cholesterol depletion inhibits clathrin-coated pit budding