Steven B. McMahon, PhD

Contact Dr. McMahon

233 South 10th Street
BLSB 609
Philadelphia, PA 19107

(215) 503-9064

Most Recent Peer-reviewed Publications

  1. Delayed Accumulation of H3K27me3 on Nascent DNA Is Essential for Recruitment of Transcription Factors at Early Stages of Stem Cell Differentiation
  2. A rare DNA contact mutation in cancer confers p53 gain-of-function and tumor cell survival via TNFAIP8 induction
  3. Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer
  4. The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness
  5. Retraction Notice to: Nuclear receptor function requires a TFTC-type histone acetyl transferase complex
  6. MYC and the control of apoptosis
  7. USP22 regulates oncogenic signaling pathways to drive lethal cancer progression
  8. The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2)
  9. P53: The TRiC Is Knowing When to Fold 'Em
  10. Acetylation of the cell-fate factor dachshund determines p53 binding and signaling modules in breast cancer
  11. Dachshund binds p53 to block the growth of lung adenocarcinoma cells
  12. A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex
  13. Dynamic regulation of mitochondrial transcription as a mechanism of cellular adaptation
  14. MYST protein acetyltransferase activity requires active site lysine autoacetylation
  15. Inhibition of the single downstream target BAG1 activates the latent apoptotic potential of MYC
  16. Enzymatic assays for assessing histone deubiquitylation activity
  17. Phosphorylation of Tip60 by GSK-3 Determines the Induction of PUMA and Apoptosis by p53
  18. The Role of Epigenetic Modifications in Cancer
  19. Myc overexpression brings out unexpected antiapoptotic effects of miR-34a
  20. Regulation of microRNA-145 by growth arrest and differentiation