2238 Aplin, Andrew E. - Thomas Jefferson University - Thomas Jefferson University
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Andrew E. Aplin, PhD

Contact Dr. Aplin

Kimmel Cancer Center
233 S. Tenth Street, Suite 522
Philadelphia, PA 19107

(215) 503-7296
(215) 923-9248 fax

Most Recent Peer-reviewed Publications

  1. Sestrin2 protein positively regulates AKT enzyme signaling and survival in human squamous cell carcinoma and melanoma cells
  2. Function-blocking ERBB3 antibody inhibits the adaptive response to RAF inhibitor
  3. Resistance to RAF inhibitors revisited
  4. FOXD3 modulates migration through direct transcriptional repression of TWIST1 in melanoma
  5. Unmet needs in melanoma research
  6. Targeting TBK1 inhibits migration and resistance to MEK inhibitors in mutant NRAS melanoma
  7. Inhibition of mutant BRAF splice variant signaling by next-generation, selective RAF inhibitors
  8. Erratum: Hippo: Hungry, hungry for melanoma invasion (Journal of Investigative Dermatology)
  9. Hippo: Hungry, hungry for melanoma invasion
  10. Adaptive resistance to RAF inhibitors in melanoma
  11. Beneficial effects of RAF inhibitor in mutant BRAF splice variant-expressing melanoma
  12. What shall we do this year?
  13. In vivo MAPK reporting reveals the heterogeneity in tumoral selection of resistance to RAF inhibitors
  14. A statement on vemurafenib-resistant melanoma
  15. Meeting report: The future of preclinical mouse models in melanoma treatment is now.
  16. Selective RAF inhibitor impairs ERK1/2 phosphorylation and growth in mutant NRAS, vemurafenib-resistant melanoma cells
  17. Melanoma adapts to RAF/MEK inhibitors through FOXD3-mediated upregulation of ERBB3
  18. Meeting report: The future of preclinical mouse models in melanoma treatment is now
  19. TWIST1 is an ERK1/2 effector that promotes invasion and regulates MMP-1 expression in human melanoma cells
  20. SHOC2 and CRAF mediate ERK1/2 reactivation in mutant NRAS-mediated resistance to RAF inhibitor
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