2AF8 Calabretta, Bruno - Thomas Jefferson University - Thomas Jefferson University
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Bruno Calabretta, MD, PhD

Contact Dr. Calabretta

Kimmel Cancer Center
233 S. Tenth Street, Suite 630 A
Philadelphia, PA 19107

(215) 503-4522

Most Recent Peer-reviewed Publications

  1. ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells
  2. Inhibition of Protooncogene Expression by Antisense Oligodeoxynucleotides: Biological and Therapeutic Implications
  3. Structure-based screen identifies a potent small molecule inhibitor of Stat5a/b with therapeutic potential for prostate cancer and chronic myeloid leukemia
  4. Monocyte-macrophage differentiation of acute myeloid leukemia cell lines by small molecules identified through interrogation of the connectivity map database
  5. Leukemia stem cells: Old concepts and new perspectives
  6. Autophagy in Chronic Myeloid Leukaemia: Stem cell survival and implication in therapy
  7. Inhibiting interactions of lysine demethylase LSD1 with snail/slug blocks cancer cell invasion
  8. Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1
  9. The p53 codon 72 Pro/Pro genotype identifies poor-prognosis neuroblastoma patients: Correlation with reduced apoptosis and enhanced senescence by the p53-72P isoform
  10. Expression of p89 c-Mybex9b, an alternatively spliced form of c-Myb, is required for proliferation and survival of p210BCR/ABL-expressing cells
  11. Phosphorylation of serine 21 modulates the proliferation inhibitory more than the differentiation inducing effects of C/EBPα in K562 cells
  12. c-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cells
  13. Suppression of autophagy by BCR/ABL
  14. TGFβ-induced c-Myb affects the expression of EMT-associated genes and promotes invasion of ER + breast cancer cells
  15. Regulation of microRNA-145 by growth arrest and differentiation
  16. Inhibition of autophagy: A new strategy to enhance sensitivity of chronic myeloid leukemia stem cells to tyrosine kinase inhibitors
  17. Expression of the transcriptional repressor Gfi-1 is regulated by C/EBPα and is involved in its proliferation and colony formation-inhibitory effects in p210BCR/ABL-expressing cells
  18. The biological effects of C/EBPα in K562 cells depend on the potency of the N-terminal regulatory region, not on specificity of the DNA binding domain
  19. Expression of slug is regulated by c-Myb and is required for invasion and bone marrow homing of cancer cells of different origin
  20. Activity of tyrosine kinase inhibitor Dasatinib in neuroblastoma cells in vitro and in orthotopic mouse model
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