bxc111

Bruno Calabretta, MD, PhD

Contact Dr. Calabretta

233 South 10th Street
BLSB 630A
Philadelphia, PA 19107

(215) 503-4522

Most Recent Peer-reviewed Publications

  1. Delayed Accumulation of H3K27me3 on Nascent DNA Is Essential for Recruitment of Transcription Factors at Early Stages of Stem Cell Differentiation
  2. Structure of Nascent Chromatin Is Essential for Hematopoietic Lineage Specification
  3. CDKN2A-independent role of BMI1 in promoting growth and survival of Ph+ acute lymphoblastic leukemia
  4. ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells
  5. Inhibition of Protooncogene Expression by Antisense Oligodeoxynucleotides: Biological and Therapeutic Implications
  6. Celecoxib inhibits proliferation and survival of chronic myelogeous leukemia (CML) cells via AMPK-dependent regulation of β-catenin and mTORC1/2
  7. Structure-based screen identifies a potent small molecule inhibitor of Stat5a/b with therapeutic potential for prostate cancer and chronic myeloid leukemia
  8. Monocyte-macrophage differentiation of acute myeloid leukemia cell lines by small molecules identified through interrogation of the connectivity map database
  9. Suppression of Invasion and Metastasis of Triple-Negative Breast Cancer Lines by Pharmacological or Genetic Inhibition of Slug Activity
  10. Leukemia stem cells: Old concepts and new perspectives
  11. Autophagy in Chronic Myeloid Leukaemia: Stem cell survival and implication in therapy
  12. Inhibiting interactions of lysine demethylase LSD1 with snail/slug blocks cancer cell invasion
  13. Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1
  14. Expression of p89 c-Mybex9b, an alternatively spliced form of c-Myb, is required for proliferation and survival of p210BCR/ABL-expressing cells
  15. Phosphorylation of serine 21 modulates the proliferation inhibitory more than the differentiation inducing effects of C/EBPα in K562 cells
  16. c-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cells
  17. The p53 codon 72 Pro/Pro genotype identifies poor-prognosis neuroblastoma patients: Correlation with reduced apoptosis and enhanced senescence by the p53-72P isoform
  18. Suppression of autophagy by BCR/ABL
  19. TGFβ-induced c-Myb affects the expression of EMT-associated genes and promotes invasion of ER+breast cancer cells
  20. Regulation of microRNA-145 by growth arrest and differentiation