bxc111

Bruno Calabretta, MD, PhD

Contact Dr. Calabretta

233 South 10th Street
BLSB 630A
Philadelphia, PA 19107

(215) 503-4522

Most Recent Peer-reviewed Publications

  1. CDKN2A-independent role of BMI1 in promoting growth and survival of Ph+ acute lymphoblastic leukemia
  2. ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells
  3. Inhibition of Protooncogene Expression by Antisense Oligodeoxynucleotides: Biological and Therapeutic Implications
  4. Celecoxib inhibits proliferation and survival of chronic myelogeous leukemia (CML) cells via AMPK-dependent regulation of β-catenin and mTORC1/2
  5. Structure-based screen identifies a potent small molecule inhibitor of Stat5a/b with therapeutic potential for prostate cancer and chronic myeloid leukemia
  6. Monocyte-macrophage differentiation of acute myeloid leukemia cell lines by small molecules identified through interrogation of the connectivity map database
  7. Suppression of Invasion and Metastasis of Triple-Negative Breast Cancer Lines by Pharmacological or Genetic Inhibition of Slug Activity
  8. Leukemia stem cells: Old concepts and new perspectives
  9. Autophagy in Chronic Myeloid Leukaemia: Stem cell survival and implication in therapy
  10. Inhibiting interactions of lysine demethylase LSD1 with snail/slug blocks cancer cell invasion
  11. Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1
  12. The p53 codon 72 Pro/Pro genotype identifies poor-prognosis neuroblastoma patients: Correlation with reduced apoptosis and enhanced senescence by the p53-72P isoform
  13. Expression of p89 c-Mybex9b, an alternatively spliced form of c-Myb, is required for proliferation and survival of p210BCR/ABL-expressing cells
  14. Phosphorylation of serine 21 modulates the proliferation inhibitory more than the differentiation inducing effects of C/EBPα in K562 cells
  15. c-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cells
  16. Suppression of autophagy by BCR/ABL
  17. TGFβ-induced c-Myb affects the expression of EMT-associated genes and promotes invasion of ER+ breast cancer cells
  18. Regulation of microRNA-145 by growth arrest and differentiation
  19. Inhibition of autophagy: A new strategy to enhance sensitivity of chronic myeloid leukemia stem cells to tyrosine kinase inhibitors
  20. Expression of the transcriptional repressor Gfi-1 is regulated by C/EBPα and is involved in its proliferation and colony formation-inhibitory effects in p210BCR/ABL-expressing cells