299F Casimiro, Mathew - Thomas Jefferson University - Thomas Jefferson University

Mathew C. Casimiro, PhD

Contact Dr. Casimiro

Kimmel Cancer Center
233 S. Tenth Street, Suite 1035
Philadelphia, PA 19107

(215) 503-9350
(215) 923-4498 fax

Most Recent Peer-reviewed Publications

  1. Time-lapse video microscopy for assessment of EYFP-Parkin aggregation as a marker for cellular mitophagy
  2. Cyclin D1 promotes androgen-dependent DNA damage repair in prostate cancer cells
  3. Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgen-independent prostate cancer cells to DNA damage
  4. The endogenous cell-fate factor dachshund restrains prostate epithelial cell migration via repression of cytokine secretion via a CXCL signaling module
  5. Kinase independent oncogenic cyclin D1
  6. Sirt1-deficient mice have hypogonadotropic hypogonadism due to defective GnRH neuronal migration
  7. Loss of sirt1 promotes prostatic intraepithelial neoplasia, reduces mitophagy, and delays park2 translocation to mitochondria
  8. Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis
  9. Cyclin D1 integrates estrogen-mediated DNA damage repair signaling
  10. Overview of cyclins D1 function in cancer and the CDK inhibitor landscape: Past and present
  11. Identification of a cyclin D1 network in prostate cancer that antagonizes epithelial-mesenchymal restraint
  12. Acetylation-defective mutants of PparĪ³ are associated with decreased lipid synthesis in breast cancer cells
  13. Cyclin D1 induction of dicer governs microRNA processing and expression in breast cancer
  14. Cyclin D1 determines estrogen signaling in the mammary gland in vivo
  15. Erratum: ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice (J Clin Invest. (2013) 123:5 (2332) 10.1172/JCI70042)
  16. Novel oncogene-induced metastatic prostate cancer cell lines define human prostate cancer progression signatures
  17. Cyclins and cell cycle control in cancer and disease
  18. Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth
  19. Cyclin D1 induces chromosomal instability
  20. ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice