2238 Casimiro, Mathew - Thomas Jefferson University - Thomas Jefferson University

Mathew C. Casimiro, PhD

Contact Dr. Casimiro

Kimmel Cancer Center
233 S. Tenth Street, Suite 1035
Philadelphia, PA 19107

(215) 503-9350
(215) 923-4498 fax

Most Recent Peer-reviewed Publications

  1. Loss of sirt1 promotes prostatic intraepithelial neoplasia, reduces mitophagy, and delays park2 translocation to mitochondria
  2. Sirt1-deficient mice have hypogonadotropic hypogonadism due to defective GnRH neuronal migration
  3. Cyclin D1 integrates estrogen-mediated DNA damage repair signaling
  4. Overview of cyclins D1 function in cancer and the CDK inhibitor landscape: Past and present
  5. Identification of a cyclin D1 network in prostate cancer that antagonizes epithelial-mesenchymal restraint
  6. Acetylation-defective mutants of Pparγ are associated with decreased lipid synthesis in breast cancer cells
  7. Cyclin D1 induction of dicer governs microRNA processing and expression in breast cancer
  8. Cyclin D1 determines estrogen signaling in the mammary gland in vivo
  9. Erratum: ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice (J Clin Invest. (2013) 123:5 (2332) 10.1172/JCI70042)
  10. Novel oncogene-induced metastatic prostate cancer cell lines define human prostate cancer progression signatures
  11. Cyclins and cell cycle control in cancer and disease
  12. Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth
  13. Cyclin D1 induces chromosomal instability
  14. ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice
  15. Mammary gland selective excision of c-Jun identifies its role in mRNA splicing
  16. Caveolin-1 overexpression enhances androgen-dependent growth and proliferation in the mouse prostate
  17. Examining the role of cyclin D1 in breast cancer
  18. Disruption of a Sirt1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formation
  19. Cell fate determination factor Dachshund reprograms breast cancer stem cell function
  20. The canonical NF-κB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion