Eischen

Christine Eischen, PhD

Contact Dr. Eischen

233 South 10th Street
BLSB 650
Philadelphia, PA 19107

(215) 503-5262

Most Recent Peer-reviewed Publications

  1. Myc enhances B-cell receptor signaling in precancerous B cells and confers resistance to Btk inhibition
  2. Mdm2 is required for survival and growth of p53-deficient cancer cells
  3. Defective replication stress response inhibits lymphomagenesis and impairs lymphocyte reconstitution
  4. Role of Mdm2 and Mdmx in DNA repair
  5. BCL-W has a fundamental role in B cell survival and lymphomagenesis
  6. The potential roles of long noncoding RNAs (lncRNA) in glioblastoma development
  7. TOX expression and role in CTCL
  8. Molecular underpinnings of HDAC inhibition revealed
  9. Histone deacetylase inhibition reveals a tumor-suppressive function of MYC-regulated miRNA in breast and lung carcinoma
  10. Interaction of MYC with host cell factor-1 is mediated by the evolutionarily conserved Myc box IV motif
  11. Genome stability requires p53
  12. miR-31 and miR-17-5p levels change during transformation of follicular lymphoma
  13. Myc Induces miRNA-mediated apoptosis in response to HDAC inhibition in hematologic malignancies
  14. MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer
  15. Haploinsufficiency of the Myc regulator Mtbp extends survival and delays tumor development in aging mice
  16. Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer
  17. SMARCAL1 maintains telomere integrity during DNA replication
  18. Potentiation of carboplatin-mediated DNA damage by the Mdm2 modulator Nutlin-3a in a humanized orthotopic breast-to-lung metastatic model
  19. Pharmacologically increasing Mdm2 inhibits DNA repair and cooperates with genotoxic agents to kill p53-inactivated ovarian cancer cells
  20. Whole-genome sequencing reveals oncogenic mutations in mycosis fungoides