Linda E. Greenbaum, MD
233 S. Tenth Street, Suite 519
Philadelphia, PA 19107
Most Recent Peer-reviewed Publications
- A genetic screen reveals Foxa3 and TNFR1 as key regulators of liver repopulation
- Protein tyrosine phosphatase of liver regeneration-1 is required for normal timing of cell cycle progression during liver regeneration
- Ablation of Foxl1-Cre-labeled hepatic progenitor cells and their descendants impairs recovery of mice from liver injury
- Dynamic recruitment of microRNAs to their mRNA targets in the regenerating liver
- Robust cellular reprogramming occurs spontaneously during liver regeneration
MD, Columbia University, College of Physicians and Surgeons, Medicine - 1980
Expertise & Research Interests
Regulation of liver regeneration: role of transcription factors for cell cycle regulation, regulation of hepatocyte proliferation by microRNAs.
Signaling pathways that regulate hepatic progenitor cell self-renewal and differentiation; role of progenitors in liver repair and development of stem cell liver cancers.
hepatocyte, liver, stem cell, transcription, fibrosis, carcinogenesis, cholangiocyte, microRNA