Karen E. Knudsen, PhD

Contact Dr. Knudsen

Sidney Kimmel Cancer Center
233 South 10th Street
BLSB 1050
Philadelphia, PA 19107

(215) 503-5692

Most Recent Peer-reviewed Publications

  1. Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer
  2. PARP Inhibitors in Prostate Cancer
  3. Sigma1 targeting to suppress aberrant androgen receptor signaling in prostate cancer
  4. Not So Fast: Cultivating miRs as Kinks in the Chain of the Cell Cycle
  5. Cell cycle-coupled expansion of AR activity promotes cancer progression
  6. Potential Impact on Clinical Decision Making via a Genome-Wide Expression Profiling: A Case Report
  7. There and back again: The middle earth of DNA repair
  8. Linking DNA Damage and Hormone Signaling Pathways in Cancer
  9. Patient-level DNA damage and repair pathway profiles and prognosis after prostatectomy for high-risk prostate cancer
  10. Downregulation of critical oncogenes by the selective SK2 Inhibitor ABC294640 hinders prostate cancer progression
  11. Development and Validation of a Scalable Next-Generation Sequencing System for Assessing Relevant Somatic Variants in Solid Tumors
  12. Novel actions of next-generation taxanes benefit advanced stages of prostate cancer
  13. Models of neuroendocrine prostate cancer
  14. Cell-cycle-dependent regulation of androgen receptor function
  15. Chromatin to Clinic: The Molecular Rationale for PARP1 Inhibitor Function
  16. Consequence of the tumor-associated conversion to cyclin D1b
  17. Hormone whodunit: Clues for solving the case of intratumor androgen production
  18. The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness
  19. Genomic prostate cancer classifier predicts biochemical failure and metastases in patients after postoperative radiation therapy
  20. PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer