16D0 Knudsen, Karen E. - Thomas Jefferson University - Thomas Jefferson University

Karen E. Knudsen, PhD

Contact Dr. Knudsen

Kimmel Cancer Center
233 S. Tenth Street, Suite 1008
Philadelphia, PA 19107

(215) 503-8574

Most Recent Peer-reviewed Publications

  1. PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer
  2. AR function in promoting metastatic prostate cancer
  3. Progesterone receptor-cyclin D1 complexes induce cell cycle-dependent transcriptional programs in breast cancer cells
  4. Targeting PARP-1 allosteric regulation offers therapeutic potential against cancer
  5. AMPed up to treat prostate cancer: Novel AMPK activators emerge for cancer therapy
  6. USP22 regulates oncogenic signaling pathways to drive lethal cancer progression
  7. Targeting cell cycle and hormone receptor pathways in cancer
  8. A hormone-DNA repair circuit governs the response to genotoxic insult
  9. Targeted radiosensitization of ETS fusion-positive prostate cancer through PARP1 inhibition
  10. IGF2 revs the steroidogenesis engine
  11. The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2)
  12. Ex vivo culture of human prostate tissue and drug development
  13. Molecular pathogenesis and progression of prostate cancer
  14. Aberrant BAF57 signaling facilitates prometastatic phenotypes
  15. The role of tumor suppressor dysregulation in prostate cancer progression
  16. Convergence of oncogenic and hormone receptor pathways promotes metastatic phenotypes
  17. Dual roles of PARP-1 promote cancer growth and progression
  18. Cyclin D1 goes metabolic: Dual functions of cyclin D1 in regulating lipogenesis
  19. Evidence for efficacy of new hsp90 inhibitors revealed by ex vivo culture of human prostate tumors
  20. The AR dependent cell cycle: Mechanisms and cancer relevance