0B68 Languino, Lucia - Thomas Jefferson University - Thomas Jefferson University

Lucia Languino, PhD

Contact Dr. Languino

Sidney Kimmel Cancer Center
233 S. Tenth Street, Suite 506
Philadelphia, PA 19107

(215) 503-3442

Most Recent Peer-reviewed Publications

  1. αvβ6 integrin promotes castrate-resistant prostate cancer through JNK1-mediated activation of andr 0B68 ogen receptor
  2. β1 integrin- and JNK-dependent tumor growth upon hypofractionated radiation
  3. Deletion of Cyclophilin D Impairs β-Oxidation and Promotes Glucose Metabolism
  4. Expression of the IL-11 Gene in Metastatic Cells Is Supported by Runx2-Smad and Runx2-cJun Complexes Induced by TGFβ1
  5. PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion
  6. Deregulation of MIR-34b/Sox2 predicts prostate cancer progression
  7. αvβ6 integrin is required for TGFβ1-mediated matrix metalloproteinase2 expression
  8. The α<inf>v</inf>β<inf>6</inf> integrin is transferred intercellularly via exosomes
  9. Survivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasion
  10. Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts
  11. Adaptive mitochondrial reprogramming and resistance to PI3K therapy
  12. Jak2-Stat5a/b Signaling Induces Epithelial-to-Mesenchymal Transition and Stem-Like Cell Properties in Prostate Cancer
  13. Integrin avb6 Promotes an osteolytic program in cancer cells by upregulating MMP2
  14. Deletion of the mitochondrial chaperone TRAP-1 uncovers global reprogramming of metabolic networks
  15. IGF-IR Promotes Prostate Cancer Growth by Stabilizing α5β1 Integrin Protein Levels
  16. Landscape of the mitochondrial Hsp90 metabolome in tumours
  17. β1 integrins mediate resistance to ionizing radiation in vivo by inhibiting c-Jun amino terminal kinase 1
  18. Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells
  19. Trop-2 promotes prostate cancer metastasis by modulating β1 integrin functions
  20. Trop-2 inhibits prostate cancer cell adhesion to fibronectin through the β1 integrin-RACK1 axis