2238 Languino, Lucia - Thomas Jefferson University - Thomas Jefferson University
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Lucia Languino, PhD

Contact Dr. Languino

Kimmel Cancer Center
233 S. Tenth Street, Suite 506
Philadelphia, PA 19107

(215) 503-3442

Most Recent Peer-reviewed Publications

  1. The αvβ6 integrin is transferred intercellularly via exosomes
  2. Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts
  3. Adaptive mitochondrial reprogramming and resistance to PI3K therapy
  4. Integrin avb6 Promotes an osteolytic program in cancer cells by upregulating MMP2
  5. Deletion of the mitochondrial chaperone TRAP-1 uncovers global reprogramming of metabolic networks
  6. IGF-IR Promotes Prostate Cancer Growth by Stabilizing α5β1 Integrin Protein Levels
  7. Landscape of the mitochondrial Hsp90 metabolome in tumours
  8. β1 integrins mediate resistance to ionizing radiation in vivo by inhibiting c-Jun amino terminal kinase 1
  9. Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells
  10. Trop-2 promotes prostate cancer metastasis by modulating β1 integrin functions
  11. Trop-2 inhibits prostate cancer cell adhesion to fibronectin through the β1 integrin-RACK1 axis
  12. Control of Tumor Bioenergetics and Survival Stress Signaling by Mitochondrial HSP90s
  13. PSA regulates androgen receptor expression in prostate cancer cells
  14. α vβ 6 integrin expression is induced in the POET and Pten pc-/- mouse models of prostatic inflammation and prostatic adenocarcinoma
  15. TRAP-1, the mitochondrial Hsp90
  16. Insulin-like growth factor 1 stimulation of androgen receptor activity requires β 1A integrins
  17. Molecular targets for radiation oncology in prostate cancer
  18. The search for a better prostate cancer biomarker
  19. Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease
  20. Preclinical characterization of mitochondria-targeted small molecule Hsp90 inhibitors, gamitrinibs, in advanced prostate cancer
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