0B68 Languino, Lucia - Thomas Jefferson University - Thomas Jefferson University
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Lucia Languino, PhD

Contact Dr. Languino

Sidney Kimmel Cancer Center
233 S. Tenth Street, Suite 506
Philadelphia, PA 19107

(215) 503-3442

Most Recent Peer-reviewed Publications

  1. Deletion of Cyclophilin D Impairs β-Oxidation and Promotes Glucose Metabolism
  2. Expression of the IL-11 Gene in Metastatic Cells Is Supported by Runx2-Smad and Runx2-cJun Complexes Induced by TGFβ1
  3. PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion
  4. Deregulation of MIR-34b/Sox2 predicts prostate cancer progression
  5. αvβ6 integrin is required for TGFβ1-mediated matrix metalloproteinase2 expression
  6. The α<inf>v</inf>β<inf>6</inf> integrin is transferred intercellularly via exosomes
  7. Survivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasion
  8. Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts
  9. Adaptive mitochondrial reprogramming and resistance to PI3K therapy
  10. Jak2-Stat5a/b Signaling Induces Epithelial-to-Mesenchymal Transition and Stem-Like Cell Properties in Prostate Cancer
  11. Integrin avb6 Promotes an osteolytic program in cancer cells by upregulating MMP2
  12. Deletion of the mitochondrial chaperone TRAP-1 uncovers global reprogramming of metabolic networks
  13. IGF-IR Promotes Prostate Cancer Growth by Stabilizing α5β1 Integrin Protein Levels
  14. Landscape of the mitochondrial Hsp90 metabolome in tumours
  15. β1 integrins mediate resistance to ionizing radiation in vivo by inhibiting c-Jun amino terminal kinase 1
  16. Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells
  17. Trop-2 promotes prostate cancer metastasis by modulating β1 integrin functions
  18. Trop-2 inhibits prostate cancer cell adhesion to fibronectin through the β1 integrin-RACK1 axis
  19. Control of Tumor Bioenergetics and Survival Stress Signaling by Mitochondrial HSP90s
  20. PSA regulates androgen receptor expression in prostate cancer cells
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