0B68 Languino, Lucia - Thomas Jefferson University - Thomas Jefferson University

Lucia Languino, PhD

Contact Dr. Languino

Kimmel Cancer Center
233 S. Tenth Street, Suite 506
Philadelphia, PA 19107

(215) 503-3442

Most Recent Peer-reviewed Publications

  1. Expression of the IL-11 Gene in Metastatic Cells Is Supported by Runx2-Smad and Runx2-cJun Complexes Induced by TGFβ1
  2. PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion
  3. Erratum: Landscape of the mitochondrial Hsp90 metabolome in tumours (Nature Communications (2013) 4 (2139) DOI:10.1038/ncomms3139)
  4. αvβ6 integrin is required for TGFβ1-mediated matrix metalloproteinase2 expression
  5. The αvβ6 integrin is transferred intercellularly via exosomes
  6. Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts
  7. Adaptive mitochondrial reprogramming and resistance to PI3K therapy
  8. Integrin avb6 Promotes an osteolytic program in cancer cells by upregulating MMP2
  9. Deletion of the mitochondrial chaperone TRAP-1 uncovers global reprogramming of metabolic networks
  10. IGF-IR Promotes Prostate Cancer Growth by Stabilizing α5β1 Integrin Protein Levels
  11. Landscape of the mitochondrial Hsp90 metabolome in tumours
  12. β1 integrins mediate resistance to ionizing radiation in vivo by inhibiting c-Jun amino terminal kinase 1
  13. Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells
  14. Trop-2 promotes prostate cancer metastasis by modulating β1 integrin functions
  15. Trop-2 inhibits prostate cancer cell adhesion to fibronectin through the β1 integrin-RACK1 axis
  16. Control of Tumor Bioenergetics and Survival Stress Signaling by Mitochondrial HSP90s
  17. PSA regulates androgen rece 05AE ptor expression in prostate cancer cells
  18. α vβ 6 integrin expression is induced in the POET and Pten pc-/- mouse models of prostatic inflammation and prostatic adenocarcinoma
  19. TRAP-1, the mitochondrial Hsp90
  20. Insulin-like growth factor 1 stimulation of androgen receptor activity requires β 1A integrins