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Steven B. McMahon, PhD

Contact Dr. McMahon

233 South 10th Street
BLSB 609
Philadelphia, PA 19107

(215) 503-9064

Most Recent Peer-reviewed Publications

  1. A rare DNA contact mutation in cancer confers p53 gain-of-function and tumor cell survival via TNFAIP8 induction
  2. Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer
  3. The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness
  4. Retraction Notice to: Nuclear receptor function requires a TFTC-type histone acetyl transferase complex
  5. MYC and the control of apoptosis
  6. USP22 regulates oncogenic signaling pathways to drive lethal cancer progression
  7. The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2)
  8. P53: The TRiC Is Knowing When to Fold 'Em
  9. Acetylation of the cell-fate factor dachshund determines p53 binding and signaling modules in breast cancer
  10. Dachshund binds p53 to block the growth of lung adenocarcinoma cells
  11. A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex
  12. Dynamic regulation of mitochondrial transcription as a mechanism of cellular adaptation
  13. MYST protein acetyltransferase activity requires active site lysine autoacetylation
  14. Inhibition of the single downstream target BAG1 activates the latent apoptotic potential of MYC
  15. Enzymatic assays for assessing histone deubiquitylation activity
  16. Phosphorylation of Tip60 by GSK-3 Determines the Induction of PUMA and Apoptosis by p53
  17. The Role of Epigenetic Modifications in Cancer
  18. Myc overexpression brings out unexpected antiapoptotic effects of miR-34a
  19. Regulation of microRNA-145 by growth arrest and differentiation
  20. Deacetylation of the DNA-binding domain regulates p53-mediated apoptosis