0B68 McMahon, Steven - Thomas Jefferson University - Thomas Jefferson University

Steven B. McMahon, PhD

Contact Dr. McMahon

Kimmel Cancer Center
233 S. Tenth Street, Suite 609
Philadelphia, PA 19107

(215) 503-9064

Most Recent Peer-reviewed Publications

  1. Dynamic regulation of mitochondrial transcription as a mechanism of cellular adaptation
  2. MYST protein acetyltransferase activity requires active site lysine autoacetylation
  3. Inhibition of the single downstream target BAG1 activates the latent apoptotic potential of MYC
  4. Enzymatic assays for assessing histone deubiquitylation activity
  5. Phosphorylation of Tip60 by GSK-3 Determines the Induction of PUMA and Apoptosis by p53
  6. Myc overexpression brings out unexpected antiapoptotic effects of miR-34a
  7. Regulation of microRNA-145 by growth arrest and differentiation
  8. Deacetylation of the DNA-binding domain regulates p53-mediated apoptosis
  9. Emerging concepts in the analysis of transcriptional targets of the MYC oncoprotein: Are the targets targetable?
  10. Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase
  11. Rise of the rival
  12. Biochemical pathways that regulate acetyltransferase and deacetylase activity in mammalian cells
  13. hMOF, a KAT(8) with Many Lives
  14. Acetylation of the DNA binding domain regulates transcription-independent apoptosis by p53
  15. Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
  16. The p53 family and programmed cell death
  17. Control of nucleotide biosynthesis by the MYC oncoprotein
  18. USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A
  19. The Putative Cancer Stem Cell Marker USP22 Is a Subunit of the Human SAGA Complex Required for Activated Transcription and Cell-Cycle Progression
  20. The ARF/oncogene pathway activates p53 acetylation within the DNA binding domain