2819 Pestell, Richard G. - Thomas Jefferson University - Thomas Jefferson University
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Richard G. Pestell, MD, PhD

Contact Dr. Pestell

Kimmel Cancer Center
233 S. Tenth Street, Suite 1050
Philadelphia, PA 19107

(215) 503-5692
(215) 503-9334 fax

Most Recent Peer-reviewed Publications

  1. The endogenous cell-fate factor dachshund restrains prostate epithelial cell migration via repression of cytokine secretion via a CXCL signaling module
  2. Antibiotics for cancer therapy
  3. Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts
  4. Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis
  5. BCL-2 family protein, BAD is down-regulated in breast cancer and inhibits cell invasion
  6. Kinase independent oncogenic cyclin D1
  7. Targeting tumor-initiating cells: Eliminating anabolic cancer stem cells with inhibitors of protein synthesis or by mimicking caloric restriction
  8. Loss of sirt1 promotes prostatic intraepithelial neoplasia, reduces mitophagy, and delays park2 translocation to mitochondria
  9. Mitochondrial mass and DNA repair in breast cancer stem cells
  10. Sirt1-deficient mice have hypogonadotropic hypogonadism due to defective GnRH neuronal migration
  11. A community effort to assess and improve drug sensitivity prediction algorithms
  12. A community computational challenge to predict the activity of pairs of compounds
  13. CCR5 receptor antagonists block metastasis to bone of v-Src oncogene-transformed metastatic prostate cancer cell lines
  14. Cyclin D1 integrates estrogen-mediated DNA damage repair signaling
  15. CAPER, a novel regulator of human breast cancer progression
  16. Role of Cancer Stem Cells in Metastasis
  17. Overview of cyclins D1 function in cancer and the CDK inhibitor landscape: Past and present
  18. Long and noncoding RNAs (lnc-RNAs) determine androgen receptor dependent gene expression in prostate cancer growth in vivo
  19. Cell fate factor DACH1 represses YB-1-mediated oncogenic transcription and translation
  20. Identification of a cyclin D1 network in prostate cancer that antagonizes epithelial-mesenchymal restraint
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