05B4 Pestell, Richard G. - Thomas Jefferson University - Thomas Jefferson University

Richard G. Pestell, MD, PhD

Contact Dr. Pestell

Kimmel Cancer Center
233 S. Tenth Street, Suite 1050
Philadelphia, PA 19107

(215) 503-5692
(215) 503-9334 fax

Most Recent Peer-reviewed Publications

  1. Time-lapse video microscopy for assessment of EYFP-Parkin aggregation as a marker for cellular mitophagy
  2. Cyclin D1 promotes androgen-dependent DNA damage repair in prostate cancer cells
  3. The endogenous cell-fate factor dachshund restrains prostate epithelial cell migration via repression of cytokine secretion via a CXCL signaling module
  4. Antibiotics for cancer therapy
  5. Kinase independent oncogenic cyclin D1
  6. Mitochondrial mass and DNA repair in breast cancer stem cells
  7. Sirt1-deficient mice have hypogonadotropic hypogonadism due to defective GnRH neuronal migration
  8. Targeting tumor-initiating cells: Eliminating anabolic cancer stem cells with inhibitors of protein synthesis or by mimicking caloric restriction
  9. Loss of sirt1 promotes prostatic intraepithelial neoplasia, reduces mitophagy, and delays park2 translocation to mitochondria
  10. Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts
  11. BCL-2 family protein, BAD is down-regulated in breast cancer and inhibits cell invasion
  12. Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis
  13. CCR5 receptor antagonists block metastasis to bone of v-Src oncogene-transformed metastatic prostate cancer cell lines
  14. A community computational challenge to predict the activity of pairs of compounds
  15. A community effort to assess and improve drug sensitivity prediction algorithms
  16. Cyclin D1 integrates estrogen-mediated DNA damage repair signaling
  17. CAPER, a novel regulator of human breast cancer progression
  18. Role of Cancer Stem Cells in Metastasis
  19. Long and noncoding RNAs (lnc-RNAs) determine androgen receptor dependent gene expression in prostate cancer growth in vivo
  20. Overview of cyclins D1 function in cancer and the CDK inhibitor landscape: Past and present