Thomas Jefferson University

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Recent Publications

Nanostructured luminescently labeled nucleic acids

RB loss promotes prostate cancer metastasis

Pattern analysis uncovers a chronic ethanol-induced disruption of the switchlike dynamics of C/EBP-β and C/EBP-α genome-wide binding during liver regeneration

Modeling cytokine regulatory network dynamics driving neuroinflammation in central nervous system disorders

Single-cell transcriptional analysis reveals novel neuronal phenotypes and interaction networks involved in the central circadian clock

Systemic leukotriene B4 receptor antagonism lowers arterial blood pressure and improves autonomic function in the spontaneously hypertensive rat

Genome-wide redistribution of MeCP2 in dorsal root ganglia after peripheral nerve injury

A novel comparative pattern analysis approach identifies chronic alcohol mediated dysregulation of transcriptomic dynamics during liver regeneration

The effects of CEP-37440, an inhibitor of focal adhesion kinase, in vitro and in vivo on inflammatory breast cancer cells

A novel comparative pattern count analysis reveals a chronic ethanol-induced dynamic shift in immediate early NF-κB genome-wide promoter binding during liver regeneration

The role of the gut-brain axis in alcohol use disorders

Erratum: Molecular variability elicits a tunable switch with discrete neuromodulatory response phenotypes (J Comput Neurosci, DOI 10.1007/s10827-015-0584-2)

Molecular variability elicits a tunable switch with discrete neuromodulatory response phenotypes

Systems analysis of non-parenchymal cell modulation of liver repair across multiple regeneration modes

In vivo zonal variation and liver cell-type specific NF-κB localization after chronic adaptation to ethanol and following partial hepatectomy

MicroRNA network changes in the brain stem underlie the development of hypertension

A novel, dynamic pattern-based analysis of NF-κB binding during the priming phase of liver regeneration reveals switch-like functional regulation of target genes

Intracellular Information Processing through Encoding and Decoding of Dynamic Signaling Features

Computational modeling of cytokine signaling in microglia

Adiponectin fine-tuning of liver regeneration dynamics revealed through cellular network modelling