Thomas Jefferson University

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Markers, Models & Mechanisms

As of January 2011, the Division’s funded research included the following:

MicroRNA Genetic Variations as Predictors of Hepatocellular Carcinoma Risk

Goal: Evaluate the effect of a pilot panel of microRNA-related genetic variations on the risk of developing hepatocellular carcinoma in patients with chronic hepatitis B infection.

Pennsylvania Department of Health funded study
Principal Investigator: Hushan Yang

Genetic Variations in Inflammation Pathway as Novel Predictive Markers for Risk of Hepatocellular Carcinoma: a Pilot Study

Goal: Evaluate a pilot panel of genetic variations in the inflammation pathway genes and risk of HBV-related HCC.

American Cancer Society-funded Institutional Research Grant
Principal Investigator: Hushan Yang

Inflammation Variants and Risk of Hepatocellular Carcinoma in HBV Patients

Goal: Assess the implication of a comprehensive panel of inflammation-related polymorphisms in HBV-HCC risk.

NIH/NCI-funded study
Principal Investigator: Hushan Yang

Predisposition to Hepatocellular Carcinoma in HBV patients – A Multigenic Approach to MicroRNA

Goal: A muti-disciplinary approach to comprehensively evaluate the involvement of microRNAs in the development of HBV-HCC.

V Foundation for Cancer Research
Principal Investigator: Hushan Yang