0B68 Martinez-Outshoorn, Ubaldo - Thomas Jefferson University - Thomas Jefferson University
Dr. Martinez-Outshoorn

Ubaldo Martinez-Outshoorn, MD

Contact Dr. Martinez-Outshoorn

925 Chestnut Street
Suite 220A
Philadelphia, PA 19107

(215) 955-8874

Most Recent Peer-reviewed Publications

  1. Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: Treating cancer like an infectious disease
  2. A two-step approach to myeloablative haploidentical transplantation: Low nonrelapse mortality and high survival confirmed in patients with earlier stage disease
  3. Targeting tumor-initiating cells: Eliminating anabolic cancer stem cells with inhibitors of protein synthesis or by mimicking caloric restriction
  4. Metabolic Asymmetry in Cancer: A "Balancing Act" that Promotes Tumor Growth
  5. JNK1 stress signaling is hyper-activated in high breast density and the tumor stroma: Connecting fibrosis, inflammation, and stemness for cancer prevention
  6. Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth
  7. The reverse warburg effect in osteosarcoma
  8. Tumor microenvironment: Introduction
  9. Tumor microenvironment and metabolic synergy in breast cancers: Critical importance of mitochondrial fuels and function
  10. Cancer metabolism: New validated targets for drug discovery
  11. Stromal glycolysis and MCT4 are hallmarks of DCIS progression to invasive breast cancer
  12. Oncogenes induce the cancer-associated fibroblast phenotype: Metabolic symbiosis and "fibroblast addiction" are new therapeutic targets for drug discovery
  13. Oncogenes and inflammation rewire host energy metabolism in the tumor microenvironment RAS and NFκB target stromal MCT4
  14. Reverse warburg effect in a patient with aggressive B-cell lymphoma: Is lactic acidosis a paraneoplastic syndrome?
  15. Compartment-specific activation of PPARγ governs breast cancer tumor growth, via metabolic reprogramming and symbiosis
  16. Cancer metabolism, stemness and tumor recurrence : MCT1 and MCT4 are functional biomarkers of metabolic symbiosis in head and neck cancer
  17. Cigarette smoke metabolically promotes cancer, via autophagy and premature aging in the host stromal microenvironment
  18. Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism Implications for breast cancer prevention
  19. Creating a tumor-resistant microenvironment Cell-mediated delivery of TNFα completely prevents breast cancer tumor formation in vivo
  20. Mitochondrial dysfunction in breast cancer cells prevents tumor growth: Understanding chemoprevention with metformin
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