16D0 Rattan, Satish - Thomas Jefferson University - Thomas Jefferson University

Satish C. Rattan, DVM

Contact Dr. Rattan

1025 Walnut Street
College Building, Room 901
Philadelphia, PA 19107

(215) 955-5614
(215) 955-5553 fax

Most Recent Peer-reviewed Publications

  1. Aging-associated oxidative stress leads to decrease in IAS tone via RhoA/ROCK downregulation
  2. Heme oxygenase-1 upregulation modulates tone and fibroelastic properties of internal anal sphincter.
  3. Smooth muscle-specific myosin phosphatase target subunit 1 (MYPT1): An important piece of the puzzle
  4. Intestinal GUCY2C prevents TGF-β secretion coordinating desmoplasia and hyperproliferation in colorectal cancer
  5. Role of PKC and RhoA/ROCK pathways in the spontaneous phasic activity in the rectal smooth muscle
  6. Smooth muscle fascicular reorientation is required for esophageal morphogenesis and dependent on Cdo
  7. Biosynthetic pathways and the role of the mas receptor in the effects of angiotensin-(1-7) in smooth muscles
  8. Effects of scleroderma antibodies and pooled human immunoglobulin on anal sphincter and colonic smooth muscle function
  9. Bioengineered human IAS reconstructs with functional and molecular properties similar to intact IAS
  10. RhoA/ROCK pathway is the major molecular determinant of basal tone in intact human internal anal sphincter
  11. Immunocytochemical evidence for PDBu-induced activation of RhoA/ROCK in human internal anal sphincter smooth muscle cells
  12. Role of rho kinase in the functional and dysfunctional tonic smooth muscles
  13. Basal internal anal sphincter tone, inhibitory neurotransmission, and other factors contributing to the maintenance of high pressures in the anal canal
  14. 3-Hydroxymethyl coenzyme A reductase inhibition attenuates spontaneous smooth muscle tone via RhoA/ROCK pathway regulated by RhoA prenylation
  15. RhoA/Rho-Kinase: Pathophysiologic and Therapeutic Implications in Gastrointestinal Smooth Muscle Tone and Relaxation
  16. Immunoglobulins from scleroderma patients inhibit the muscarinic receptor activation in internal anal sphincter smooth muscle cells
  17. Arachidonic acid metabolites follow the preferential course of cyclooxygenase pathway for the basal tone in the internal anal sphincter
  18. Role of RHO Kinase in Gastrointestinal Motility
  19. COX-1 vs. COX-2 as a determinant of basal tone in the internal anal sphincter
  20. Sympathetic (Adrenergic) Innervation Modulates But Does Not Generate Basal Tone in the Internal Anal Sphincter Smooth Muscle