0B68 McKenzie, Steven E. - Thomas Jefferson University - Thomas Jefferson University

Steven E. McKenzie, MD, PhD

Contact Dr. McKenzie

1020 Locust Street
Suite 394
Philadelphia, PA 19107

(215) 955-3900
(215) 923-3836 fax

Most Recent Peer-reviewed Publications

  1. Platelet 12-LOX is essential for FcγRIIa-mediated platelet activation
  2. MicroRNA expression differences in human hematopoietic cell lineages enable regulated transgene expression
  3. Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics
  4. The human platelet: Strong transcriptome correlations among individuals associate weakly with the platelet proteome
  5. Identification of a developmental gene expression signature, including hox genes, for the normal human colonic crypt stem cell niche: Overexpression of the signature parallels stem cell overpopulation during colon tumorigenesis
  6. Advances in the pathophysiology and treatment of heparin-induced thrombocytopenia
  7. Tyrosine phosphorylation on spleen tyrosine kinase (Syk) is differentially regulated in human and murine platelets by protein kinase C isoforms
  8. MicroRNAs in platelet production and activation
  9. Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo
  10. The complex transcriptional landscape of the anucleate human platelet
  11. Monocytes in HIT: An evolving story
  12. CalDAG-GEFI deficiency protects mice in a novel model of FcγRIIA-mediated thrombosis and thrombocytopenia
  13. Safety and pharmacokinetics of subcutaneously administered recombinant activated factor VII (rFVIIa)
  14. PRT-060318, a novel Syk inhibitor, prevents heparin-induced thrombocytopenia and thrombosis in a transgenic mouse model
  15. Amelioration of murine immune thrombocytopenia by CD44 antibodies: A potential therapy for ITP?
  16. Dominant expression of the inhibitory FcγRIIB prevents antigen presentation by murine plasmacytoid dendritic cells
  17. The clot thickens (or not)
  18. Thrombopoietin following transfusion of platelets in preterm neonates
  19. The yin and yang of Fcγ receptors in ITP
  20. Heparin-induced thrombocytopenia: An autoimmune disorder regulated through dynamic autoantigen assembly/disassembly