0B68 McKenzie, Steven E. - Thomas Jefferson University - Thomas Jefferson University

Steven E. McKenzie, MD, PhD

Contact Dr. McKenzie

1020 Locust Street
Suite 394
Philadelphia, PA 19107

(215) 955-3900
(215) 923-3836 fax

Most Recent Peer-reviewed Publications

  1. The human platelet: Strong transcriptome correlations among individuals associate weakly with the platelet proteome
  2. Identification of a developmental gene expression signature, including hox genes, for the normal human colonic crypt stem cell niche: Overexpression of the signature parallels stem cell overpopulation during colon tumorigenesis
  3. Tyrosine phosphorylation on spleen tyrosine kinase (Syk) is differentially regulated in human and murine platelets by protein kinase C isoforms
  4. MicroRNAs in platelet production and activation
  5. Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo
  6. The complex transcriptional landscape of the anucleate human platelet
  7. Monocytes in HIT: An evolving story
  8. CalDAG-GEFI deficiency protects mice in a novel model of FcγRIIA-mediated thrombosis and thrombocytopenia
  9. Safety and pharmacokinetics of subcutaneously administered recombinant activated factor VII (rFVIIa)
  10. PRT-060318, a novel Syk inhibitor, prevents heparin-induced thrombocytopenia and thrombosis in a transgenic mouse model
  11. Amelioration of murine immune thrombocytopenia by CD44 antibodies: A potential therapy for ITP?
  12. Dominant expression of the inhibitory FcγRIIB prevents antigen presentation by murine plasmacytoid dendritic cells
  13. The clot thickens (or not)
  14. Thrombopoietin following transfusion of platelets in preterm neonates
  15. The yin and yang of Fcγ receptors in ITP
  16. Heparin-induced thrombocytopenia: An autoimmune disorder regulated through dynamic autoantigen assembly/disassembly
  17. Cholesterol enrichment of human monocyte/macrophages induces surface exposure of phosphatidylserine and the release of biologically-active tissue factor-positive microvesicles
  18. Prothrombotic factors enhance heparin-induced thrombocytopenia and thrombosis in vivo in a mouse model
  19. Platelet FcγRIIA binds and internalizes IgG-containing complexes
  20. Development of spontaneous multisystem autoimmune disease and hypersensitivity to antibody-induced inflammation in Fcγ receptor IIa-transgenic mice