111C Faber, Milosz A. - Thomas Jefferson University - Thomas Jefferson University

Milosz A. Faber, PhD

Contact Dr. Faber

1020 Locust Street
Jefferson Alumni Hall, Room 465
Philadelphia, PA 19107

(215) 503-4153
(215) 923-7144 fax

Most Recent Peer-reviewed Publications

  1. Expression of interferon gamma by a recombinant rabies virus strongly attenuates the pathogenicity of the virus via induction of type I interferon
  2. Pre- and post-exposure safety and efficacy of attenuated rabies virus vaccines are enhanced by their expression of IFNγ
  3. Limited brain metabolism changes differentiate between the progression and clearance of rabies virus
  4. Intramuscular inoculation of mice with the live-attenuated recombinant rabies virus TriGAS results in a transient infection of the draining lymph nodes and a robust, long-lasting protective immune response against rabies
  5. Postexposure treatment with the live-attenuated rabies virus (rv) Vaccine trigas triggers the clearance of wild-type rv from the central nervous system (cns) Through the rapid induction of genes relevant to adaptive immunity in cns tissues
  6. Immunogenicity and safety of recombinant rabies viruses used for oral vaccination of stray dogs and wildlife
  7. Effective preexposure and postexposure prophylaxis of rabies with a highly attenuated recombinant rabies virus
  8. Concepts in the pathogenesis of rabies
  9. Infection of monocytes or immature dendritic cells (DCs) with an attenuated rabies virus results in DC maturation and a strong activation of the NFκB signaling pathway
  10. Dominance of a nonpathogenic glycoprotein gene over a pathogenic glycoprotein gene in rabies virus
  11. A single immunization with a recombinant canine adenovirus expressing the rabies virus G protein confers protective immunity against rabies in mice
  12. Overexpression of tumor necrosis factor alpha by a recombinant rabies virus attenuates replication in neurons and prevents lethal infection in mice
  13. A single amino acid change in rabies virus glycoprotein increases virus spread and enhances virus pathogenicity
  14. A single immunization with a rhabdovirus-based vector expressing severe acute respiratory syndrome coronavirus (SARS-CoV) S protein results in the production of high levels of SARS-CoV-neutralizing antibodies
  15. Novel rabies virus-neutralizing epitope recognized by human monoclonal antibody: Fine mapping and escape mutant analysis
  16. In vitro growth and stability of recombinant rabies viruses designed for vaccination of wildlife
  17. Identification of viral genomic elements responsible for rabies virus neuroinvasiveness
  18. Development of a cocktail of recombinant-expressed human rabies virus-neutralizing monoclonal antibodies for postexposure prophylaxis of rabies
  19. New approaches to the prevention and eradication of rabies
  20. Overexpression of the rabies virus glycoprotein results in enhancement of apoptosis and antiviral immune response