2238 Sykulev, Yuri K. - Thomas Jefferson University - Thomas Jefferson University

Yuri K. Sykulev, MD, PhD

Contact Dr. Sykulev

233 South Tenth Street
Bluemle Life Sciences Building, Room 706
Philadelphia, PA 19107

(215) 503-4530
(215) 923-4153 fax

Most Recent Peer-reviewed Publications

  1. Integrins influence the size and dynamics of signaling microclusters in a Pyk2-dependent manner
  2. Integrin receptors on tumor cells facilitate NK cell-mediated antibody-dependent cytotoxicity
  3. Core-based lipid nanoparticles as a nanoplatform for delivery of near-infrared fluorescent imaging agents
  4. Evidence that the density of self peptide-MHC ligands regulates T-cell receptor signaling
  5. Enteric alpha defensins in norm and pathology.
  6. The mechanisms of inactivation of the Tag7-Hsp70 cytotoxic complex
  7. Enteric alpha defensins in norm and pathology
  8. Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes
  9. Quantum dots as a unique nanoscaffold to mimic membrane receptor clustering
  10. T cell receptor signaling kinetics takes the stage
  11. A novel composite immunotoxin that suppresses rabies virus production by the infected cells
  12. Changing separating distances between immune receptors as a sensitive mechanism regulating T-cell activation
  13. Kinetics of Early T Cell Receptor Signaling Regulate the Pathway of Lytic Granule Delivery to the Secretory Domain
  14. Can oligomeric T-cell receptor be used as a tool to detect viral peptide epitopes on infected cells?
  15. How a T cell receptor-like antibody recognizes major histocompatibility complex-bound peptide
  16. Protein kinase Cθ regulates stability of the peripheral adhesion ring junction and contributes to the sensitivity of target cell lysis by CTL
  17. Tpl2 and E 061D RK transduce antiproliferative T cell receptor signals and inhibit transformation of chronically stimulated T cells
  18. Quantum dot/peptide-MHC biosensors reveal strong CD8-dependent cooperation between self and viral antigens that augment the T cell response
  19. Structural basis for degenerate recognition of natural HIV peptide variants by cytotoxic lymphocytes
  20. Target Cell Contributions to Cytotoxic T Cell Sensitivity