Yuri K. Sykulev, MD, PhD

Contact Dr. Sykulev

233 South Tenth Street
Bluemle Life Sciences Building, Room 706
Philadelphia, PA 19107

(215) 503-4530
(215) 923-4153 fax

Most Recent Peer-reviewed Publications

  1. Evaluating frequency and quality of pathogen-specific T cells
  2. Integrins influence the size and dynamics of signaling microclusters in a Pyk2-dependent manner
  3. Herman N. Eisen: Mentor to many
  4. Integrin receptors on tumor cells facilitate NK cell-mediated antibody-dependent cytotoxicity
  5. Evidence that the density of self peptide-MHC ligands regulates T-cell receptor signaling
  6. Enteric alpha defensins in norm and pathology.
  7. The mechanisms of inactivation of the Tag7-Hsp70 cytotoxic complex
  8. Enteric alpha defensins in norm and pathology
  9. Role of the MTOC in T cell effector functions
  10. Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes
  11. Quantum dots as a unique nanoscaffold to mimic membrane receptor clustering
  12. T cell receptor signaling kinetics takes the stage
  13. A novel composite immunotoxin that suppresses rabies virus production by the infected cells
  14. Changing separating distances between immune receptors as a sensitive mechanism regulating T-cell activation
  15. Kinetics of Early T Cell Receptor Signaling Regulate the Pathway of Lytic Granule Delivery to the Secretory Domain
  16. Can oligomeric T-cell receptor be used as a tool to detect viral peptide epitopes on infected cells?
  17. How a T cell receptor-like antibody recognizes major histocompatibility complex-bound peptide
  18. Protein kinase Cθ regulates stability of the peripheral adhesion ring junction and contributes to the sensitivity of target cell lysis by CTL
  19. Tpl2 and ERK transduce antiproliferative T cell receptor signals and inhibit transformation of chronically stimulated T cells
  20. Quantum dot/peptide-MHC biosensors reveal strong CD8-dependent cooperation between self and viral antigens that augment the T cell response