0B68 Sykulev, Yuri K. - Thomas Jefferson University - Thomas Jefferson University

Yuri K. Sykulev, MD, PhD

Contact Dr. Sykulev

233 South Tenth Street
Bluemle Life Sciences Building, Room 706
Philadelphia, PA 19107

(215) 503-4530
(215) 923-4153 fax

Most Recent Peer-reviewed Publications

  1. Integrin receptors on tumor cells facilitate NK cell-mediated antibody-dependent cytotoxicity
  2. Core-based lipid nanoparticles as a nanoplatform for delivery of near-infrared fluorescent imaging agents
  3. Evidence that the density of self peptide-MHC ligands regulates T-cell receptor signaling
  4. Enteric alpha defensins in norm and pathology.
  5. The mechanisms of inactivation of the Tag7-Hsp70 cytotoxic complex
  6. Enteric alpha defensins in norm and pathology
  7. Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes
  8. Quantum dots as a unique nanoscaffold to mimic membrane receptor clustering
  9. T cell receptor signaling kinetics takes the stage
  10. A novel composite immunotoxin that suppresses rabies virus production by the infected cells
  11. Changing separating distances between immune receptors as a sensitive mechanism regulating T-cell activation
  12. Kinetics of Early T Cell Receptor Signaling Regulate the Pathway of Lytic Granule Delivery to the Secretory Domain
  13. Can oligomeric T-cell receptor be used as a tool to detect viral peptide epitopes on infected cells?
  14. How a T cell receptor-like antibody recognizes major histocompatibility complex-bound peptide
  15. Protein kinase Cθ regulates stability of the peripheral adhesion ring junction and contributes to the sensitivity of target cell lysis by CTL
  16. Tpl2 and ERK transduce antiproliferative T cell receptor signals and inhibit transformation of chronically stimulated T cells
  17. Quantum dot/peptide-MHC biosensors reveal strong CD8-dependent cooperation between self and viral antigens that augment the T cell response
  18. Structural basis for degenerate recognition of natural HIV peptide variants by cytotoxic lymphocytes
  19. Target Cell Contributions to Cytotoxic T Cell Sensitivity
  20. Antagonism of HIV-specific CD4+ T cells by C-terminal truncation of a minimum epitope