Jonathan Brody, PhD

Contact Dr. Brody

1015 Walnut Street
Room 623
Philadelphia, PA 19107

(215) 955-2693

Most Recent Peer-reviewed Publications

  1. Posttranscriptional upregulation of IDH1 by HuR establishes a powerful survival phenotype in pancreatic cancer cells
  2. CRISPR knockout of the HuR gene causes a xenograft lethal phenotype
  3. BRCA2 secondary mutation-mediated resistance to platinum and PARP inhibitor-based therapy in pancreatic cancer
  4. Therapeutic implications of molecular subtyping for pancreatic cancer
  5. Therapeutic Implications of Molecular Subtyping for Pancreatic Cancer
  6. A pilot study evaluating concordance between blood-based and patient-matched tumor molecular testing within pancreatic cancer patients participating in the Know Your Tumor (KYT) initiative
  7. WEE1 inhibition in pancreatic cancer cells is dependent on DNA repair status in a context dependent manner
  8. The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells
  9. Insights from HuR biology point to potential improvement for second-line ovarian cancer therapy
  10. Delivery of Therapeutics Targeting the mRNA Binding Protein HuR Using 3DNA Nanocarriers Suppresses Ovarian Tumor Growth
  11. The landscape of pancreatic cancer therapeutic resistance mechanisms
  12. Personalized therapy for Pancreatic Cancer: Do we need better targets, arrows, or both?
  13. Genetic Diversity of Pancreatic Ductal Adenocarcinoma and Opportunities for Precision Medicine
  14. HuR contributes to TRAIL resistance by restricting death receptor 4 expression in pancreatic cancer cells
  15. Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis
  16. Current standards and novel treatment options for metastatic pancreatic adenocarcinoma
  17. Current Standards and Novel Treatment Options for Metastatic Pancreatic Adenocarcinoma
  18. Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- And tissue-specific microRNAs
  19. Cancer of the pancreas
  20. Novel targets in pancreatic cancer research