Jonathan Brody, PhD

Contact Dr. Brody

1015 Walnut Street
Room 623
Philadelphia, PA 19107

(215) 955-2693

Most Recent Peer-reviewed Publications

  1. WEE1 inhibition in pancreatic cancer cells is dependent on DNA repair status in a context dependent manner
  2. The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells
  3. Insights from HuR biology point to potential improvement for second-line ovarian cancer therapy
  4. Delivery of Therapeutics Targeting the mRNA Binding Protein HuR Using 3DNA Nanocarriers Suppresses Ovarian Tumor Growth
  5. The landscape of pancreatic cancer therapeutic resistance mechanisms
  6. HuR contributes to TRAIL resistance by restricting death receptor 4 expression in pancreatic cancer cells
  7. Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis
  8. Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- And tissue-specific microRNAs
  9. Cancer of the pancreas
  10. Novel targets in pancreatic cancer research
  11. Selective impact of CDK4/6 suppression on patient-derived models of pancreatic cancer
  12. Studying RNA-binding protein interactions with target mRNAs in eukaryotic cells: Native ribonucleoprotein immunoprecipitation (RIP) assays
  13. Targeting the mRNA-binding protein HuR impairs malignant characteristics of pancreatic ductal adenocarcinoma cells
  14. MUC1 promoter-driven DTA as a targeted therapeutic strategy against pancreatic cancer
  15. Upgrading gemcitabine with recycled kinase inhibitors
  16. Argonaute CLIP-Seq reveals miRNA targetome diversity across tissue types
  17. HuR posttranscriptionally regulates WEE1: Implications for the DNA damage response in pancreatic cancer cells
  18. Commentary : Fusing transcriptomics to progressive prostate cancer
  19. PARP inhibitors for chemoprevention - Letter
  20. Targeting PARP-1 allosteric regulation offers therapeutic potential against cancer