0B68 Brody, Jonathan - Thomas Jefferson University - Thomas Jefferson University

Jonathan Brody, PhD

Contact Dr. Brody

1015 Walnut Street
Room 623
Philadelphia, PA 19107

(215) 955-2693

Most Recent Peer-reviewed Publications

  1. WEE1 inhibition in pancreatic cancer cells is dependent on DNA repair status in a context dependent manner
  2. The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells
  3. Insights from HuR biology point to potential improvement for second-line ovarian cancer therapy
  4. Delivery of Therapeutics Targeting the mRNA Binding Protein HuR Using 3DNA Nanocarriers Suppresses Ovarian Tumor Growth
  5. The landscape of pancreatic cancer therapeutic resistance mechanisms
  6. HuR contributes to TRAIL resistance by restricting death receptor 4 expression in pancreatic cancer cells
  7. Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- And tissue-specific microRNAs
  8. Cancer of the pancreas
  9. Novel targets in pancreatic cancer research
  10. Studying RNA-binding protein interactions with target mRNAs in eukaryotic cells: Native ribonucleoprotein immunoprecipitation (RIP) assays
  11. Selective impact of CDK4/6 suppression on patient-derived models of pancreatic cancer
  12. Targeting the mRNA-binding protein HuR impairs malignant characteristics of pancreatic ductal adenocarcinoma cells
  13. MUC1 promoter-driven DTA as a targeted therapeutic strategy against pancreatic cancer
  14. Upgrading gemcitabine with recycled kinase inhibitors
  15. Argonaute CLIP-Seq reveals miRNA targetome diversity across tissue types
  16. HuR posttranscriptionally regulates WEE1: Implications for the DNA damage response in pancreatic cancer cells
  17. Commentary : Fusing transcriptomics to progressive prostate cancer
  18. PARP inhibitors for chemoprevention - Letter
  19. Targeting PARP-1 allosteric regulation offers therapeutic potential against cancer
  20. dCK expression correlates with 5-fluorouracil efficacy and HuR cytoplasmic expression in pancreatic cancer: A dual-institutional follow-up with the RTOG 9704 trial