0B68 Daniel, Rene - Thomas Jefferson University - Thomas Jefferson University

Rene Daniel, MD, PhD

Contact Dr. Daniel

1015 Walnut Street
Room 807B
Philadelphia, PA 19107

(215) 503-5725

Most Recent Peer-reviewed Publications

  1. Understanding lentiviral vector chromatin targeting: Working to reduce insertional mutagenic potential for gene therapy
  2. Stem cells and aging: A chicken-or-the-egg issue?
  3. Pyruvate kinase expression (PKM1 and PKM2) in cancer associated fibroblasts drives stromal nutrient production and tumor growth
  4. Proliferating cell nuclear antigen is required for loading of the SMCX/KMD5C histone demethylase onto chromatin
  5. Host Factors that affect Provirus Stability and Silencing
  6. Up-regulation of HIV-1 transduction in nondividing cells by double-strand DNA break-inducing agents
  7. HIV-1 integration site preferences in pluripotent cells
  8. A role for the histone deacetylase HDAC4 in the life-cycle of HIV-1-based vectors
  9. A role for the Werner syndrome protein in epigenetic inactivation of the pluripotency factor Oct4
  10. Modification of integration site preferences of an HIV-1-based vector by expression of a novel synthetic protein
  11. HIV-1 Tat and AIDS-associated cancer: Targeting the cellular anti-cancer barrier?
  12. Integration site selection by retroviral vectors: Molecular mechanism and clinical consequences
  13. ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis (Journal of Biological Chemistry (2008) 283, (6572-6583))
  14. Abnormal cytokinesis after X-irradiation in tumor cells that override the G2 DNA damage checkpoint
  15. Evidence that the Nijmegen breakage syndrome protein, an early sensor of double-strand DNA breaks (DSB), is involved in HIV-1 post-integration repair by recruiting the ataxia telangiectasia-mutated kinase in a process similar to, but distinct from, cellular DSB repair
  16. ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis
  17. Pentoxifylline suppresses transduction by HIV-1-based vectors
  18. DNA repair in HIV-1 infection: A case for inhibitors of cellular co-factors?
  19. Following the path of the virus: the exploitation of host DNA repair mechanisms by retroviruses.
  20. Exogenous IL-7 induces Fas-mediated human neuronal apoptosis: Potential effects during human immunodeficiency virus type 1 infection