Adam Snook, PhD

Adam Snook, PhD

Contact Dr. Snook

1020 Locust Street
JAH 368E
Philadelphia, PA 19107

(215) 503-7445
(215) 955-7006 fax

Most Recent Peer-reviewed Publications

  1. Immunotherapy in Colorectal Cancer: Where Are We Now?
  2. The heat-stable enterotoxin receptor, guanylyl cyclase C, as a pharmacological target in colorectal cancer immunotherapy: A bench-to-bedside current report
  3. GUCY2C signaling opposes the acute radiation-induced GI syndrome
  4. ST-producing E. Coli oppose carcinogen-induced colorectal tumorigenesis in mice
  5. Guanylate cyclase C as a target for prevention, detection, and therapy in colorectal cancer
  6. The swinging pendulum of cancer immunotherapy personalization
  7. Prime-boost immunization eliminates metastatic colorectal cancer by producing high-Avidity effector CD8+T cells
  8. siRNA-Encapsulated Hybrid Nanoparticles Target Mutant K-ras and Inhibit Metastatic Tumor Burden in a Mouse Model of Lung Cancer
  9. RB loss promotes prostate cancer metastasis
  10. EXECUTIVE INTERVIEW - Viral gene: Protein-targeting cancer vaccine could boost survival rates
  11. GUCY2C maintains intestinal LGR5+stem cells by opposing ER stress
  12. Preclinical Evaluation of a Replication-Deficient Recombinant Adenovirus Serotype 5 Vaccine Expressing Guanylate Cyclase C and the PADRE T-helper Epitope
  13. GUCY2C-directed CAR-T cells oppose colorectal cancer metastases without autoimmunity
  14. Guanylyl cyclase C hormone axis at the intersection of obesity and colorectal cancer
  15. Targeting guanylate cyclase C in colorectal cancer: Where are we now?
  16. Obesity-induced colorectal cancer is driven by caloric silencing of the guanylin-GUCY2C paracrine signaling axis
  17. A novel role for Cish in the inhibition of TCR signaling
  18. Biodistribution and Pharmacokinetics Study of siRNA-loaded Anti-NTSR1-mAb-functionalized Novel Hybrid Nanoparticles in a Metastatic Orthotopic Murine Lung Cancer Model
  19. Calorie-induced ER stress suppresses uroguanylin satiety signaling in diet-induced obesity
  20. Intestinal enteroids model guanylate cyclase C-dependent secretion induced by heat-stable enterotoxins