0B68 Rafi, Mohammed A - Thomas Jefferson University - Thomas Jefferson University
Mohammed A. Rafi

Mohammed A. Rafi,

Contact Dr. Rafi

1020 Locust Street
Suite 393 JAH
Philadelphia, PA 19107

(215) 503-5715
(215) 923-7747 fax

Most Recent Peer-reviewed Publications

  1. Krabbe disease: Are certain mutations disease-causing only when specific polymorphisms are present or when inherited in trans with specific second mutations?
  2. Lysosomal storage diseases: Heterogeneous group of disorders
  3. Sixteen novel mutations in the arylsulfatase A gene causing metachromatic leukodystrophy
  4. Extended normal life after AAVrh10-mediated gene therapy in the mouse model of krabbe disease
  5. Gene and stem cell therapy: Alone or in combination?
  6. Combined effects of hyperglycemic conditions and HIV-1 Nef: A potential model for induced HIV neuropathogenesis
  7. Effects of treatments on inflammatory and apoptotic markers in the CNS of mice with globoid cell leukodystrophy
  8. Significant correction of pathology in brains of twitcher mice following injection of genetically modified mouse neural progenitor cells
  9. A single mutation in the GALC gene is responsible for the majority of late onset Krabbe disease patients in the Catan 111C ia (Sicily, Italy) region.
  10. HIV-1 Vpr potently induces programmed cell death in the CNS in vivo
  11. Insulin-like growth factor-1 provides protection against psychosine-induced apoptosis in cultured mouse oligodendrocyte progenitor cells using primarily the PI3K/Akt pathway
  12. AAV2/5 vector expressing galactocerebrosidase ameliorates CNS disease in the murine model of globoid-cell leukodystrophy more efficiently than AAV2
  13. Biochemical and pathological evaluation of long-lived mice with globoid cell leukodystrophy after bone marrow transplantation
  14. AAV-Mediated expression of galactocerebrosidase in brain results in attenuated symptoms and extended life span in murine models of globoid cell leukodystrophy
  15. Generation of transgenic mice expressing insulin-like growth factor-1 under the control of the myelin basic protein promoter: Increased myelination and potential for studies on the effects of increased IGF-1 on experimentally and genetically induced demyelination
  16. Disease-causing mutations in cis with the common arylsulfatase A pseudodeficiency allele compound the difficulties in accurately identifying patients and carriers of metachromatic leukodystrophy
  17. Mutation analysis of feline Niemann-Pick C1 disease
  18. Peripheral neuropathy with hypomyelinating features in adult-onset Krabbe's disease
  19. Retrovirus-mediated gene transfer and galactocerebrosidase uptake into twitcher glial cells results in appropriate localization and phenotype correction
  20. Generation of a mouse with low galactocerebrosidase activity by gene targeting: A new model of globoid cell leukodystrophy (Krabbe disease)
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