2A61 Wenger, David A - Thomas Jefferson University - Thomas Jefferson University
David A. Wenger, PhD

David A. Wenger, PhD

Contact Dr. Wenger

1020 Locust Street
Room 394
Philadelphia, PA 19107

(215) 955-1666
(215) 955-9554 fax

Most Recent Peer-reviewed Publications

  1. Krabbe disease: Are certain mutations disease-causing only when specific polymorphisms are present or when inherited in trans with specific second mutations?
  2. Patient with unilateral white matter involvement does not have Krabbe disease
  3. Metachromatic leukodystrophy: A case of triplets with the late infantile variant and a systematic review of the literature
  4. Effects of treatments on inflammatory and apoptotic markers in the CNS of mice with globoid cell leukodystrophy
  5. The long-term outcomes of presymptomatic infants transplanted for Krabbe disease: Report of the workshop held on July 11 and 12, 2008, Holiday Valley, New York
  6. Significant correction of pathology in brains of twitcher mice following injection of genetically modified mouse neural progenitor cells
  7. Newborn Screening for Krabbe Disease: the New York State Model
  8. Sphingomyelinase deficiency (Niemann-Pick disease) in a Hereford calf
  9. Brain proton magnetic resonance spectroscopy and neuromuscular pathology in a patient with GM1 gangliosidosis
  10. A single mutation in the GALC gene is responsible for the majority of late onset Krabbe disease patients in the Catania (Sicily, Italy) region.
  11. Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease
  12. Intrinsic resistance of neural stem cells to toxic metabolites may make them well suited for cell non-autonomous disorders: Evidence from a mouse model of Krabbe leukodystrophy
  13. Galactocerebrosidase-deficient oligodendrocytes maintain stable central myelin by exogenous replacement of the missing enzyme in mice
  14. Insulin-like growth factor-1 provides protection against psychosine-induced apoptosis in cultured mouse oligodendrocyte progenitor cells using primarily the PI3K/Akt pathway
  15. Abnormal neuronal metabolism and storage in mucopolysaccharidosis type VI (Maroteaux-Lamy) disease
  16. AAV2/5 vector expressing galactocerebrosidase ameliorates CNS disease in the murine model of globoid-cell leukodystrophy more efficiently than AAV2
  17. Biochemical and pathological evaluation of long-lived mice with globoid cell leukodystrophy after bone marrow transplantation
  18. Transplantation of umbilical-cord blood in babies with infantile Krabbe's disease
  19. AAV-Mediated expression of galactocerebrosidase in brain results in attenuated symptoms and extended life span in murine models of globoid cell leukodystrophy
  20. Clinical, biochemical, and molecular diagnosis of a free sialic acid storage disease patient of moderate severity
0