0B68 Wenger, David A - Thomas Jefferson University - Thomas Jefferson University
David A. Wenger, PhD

David A. Wenger, PhD

Contact Dr. Wenger

1020 Locust Street
Room 394
Philadelphia, PA 19107

(215) 955-1666
(215) 955-9554 fax

Most Recent Peer-reviewed Publications

  1. Long-term improvements in lifespan and pathology in CNS and PNS after BMT plus one intravenous injection of AAVrh10-GALC in twitcher mice
  2. Enzyme replacement therapy of a novel humanized mouse model of globoid cell leukodystrophy
  3. Intravenous injection of AAVrh10-GALC after the neonatal period in twitcher mice results in significant expression in the central and peripheral nervous systems and improvement of clinical features
  4. Krabbe Disease: Globoid Cell Leukodystrophy
  5. Krabbe disease: Are certain mutations disease-causing only when specific polymorphisms are present or when inherited in trans with specific second mutations?
  6. Iminosugar-based galactoside mimics as inhibitors of galactocerebrosidase: SAR studies and comparison with other lysosomal galactosidases
  7. Lysosomal storage diseases: Heterogeneous group of disorders
  8. Sixteen novel mutations in the arylsulfatase A gene causing metachromatic leukodystrophy
  9. Sphingomyelin lipidosis (Niemann-Pick Disease) in a juvenile raccoon (Procyon lotor)
  10. GM2 Gangliosidosis (B Variant) in Two Japanese Chins: Clinical, Magnetic Resonance Imaging and Pathological Characteristics
  11. Determination of psychosine concentration in dried blood spots from newborns that were identified via newborn screening to be at risk for Krabbe disease
  12. GM2 gangliosidosis associated with a HEXA missense mutation in Japanese Chin dogs: A poten 05B4 tial model for Tay Sachs disease
  13. Metachromatic Leukodystrophy and Globoid Cell Leukodystrophy
  14. Extended normal life after AAVrh10-mediated gene therapy in the mouse model of krabbe disease
  15. Patient with unilateral white matter involvement does not have Krabbe disease
  16. Metachromatic leukodystrophy: A ca 07D1 se of triplets with the late infantile variant and a systematic review of the literature
  17. Effects of treatments on inflammatory and apoptotic markers in the CNS of mice with globoid cell leukodystrophy
  18. The long-term outcomes of presymptomatic infants transplanted for Krabbe disease: Report of the workshop held on July 11 and 12, 2008, Holiday Valley, New York
  19. Significant correction of pathology in brains of twitcher mice following injection of genetically modified mouse neural progenitor cells
  20. Newborn Screening for Krabbe Disease: the New York State Model