0B68 Iacovitti, Lorraine - Thomas Jefferson University - Thomas Jefferson University
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Lorraine Iacovitti, PhD

Contact Dr. Iacovitti

900 Walnut St.
Suite 462
Philadelphia, PA 19107

(215) 955-8118
(215) 955-2992 fax

Most Recent Peer-reviewed Publications

  1. Evolutionary conservation of an atypical glucocorticoid-responsive element in the human tyrosine hydroxylase gene
  2. BMP and TGF-Β pathway mediators are critical upstream regulators of Wnt signaling during midbrain dopamine differentiation in human pluripotent stem cells
  3. Tracking Transplanted Bone Marrow Stem Cells and Their Effects in the Rat MCAO Stroke Model
  4. Gremlin is a novel VTA derived neuroprotective factor for dopamine neurons
  5. Changes in host blood factors and brain glia accompanying the functional recovery after systemic administration of bone marrow stem cells in ischemic stroke rats
  6. Cell-autonomous alteration of dopaminergic transmission by wild type and mutant (ΔE) TorsinA in transgenic mice
  7. VTA neurons show a potentially protective transcriptional response to MPTP
  8. Dopaminergic neurons derived from human induced pluripotent stem cells survive and integrate into 6-OHDA-lesioned rats
  9. Heterotopically transplanted CVO neural stem cells generate neurons and migrate with SVZ cells in the adult mouse brain
  10. Genetic ablation of caveolin-1 increases neural stem cell proliferation in the subventricular zone (SVZ) of the adult mouse brain
  11. Functional heterogeneity at dopamine release sites
  12. Human amniotic fluid stem cells do not differentiate into dopamine neurons in vitro or after transplantation in vivo
  13. Circumventricular organs: A novel site of neural stem cells in the adult brain
  14. The role of Lmx1a in the differentiation of human embryonic stem cells into midbrain dopamine neurons in culture and after transplantation into a Parkinson's disease model
  15. Expression of the LRRK2 gene in the midbrain dopaminergic neurons of the substantia nigra
  16. Transcription and epigenetic profile of the promoter, first exon and first intron of the human tyrosine hydroxylase gene
  17. A protocol for the differentiation of human embryonic stem cells into dopaminergic neurons using only chemically defined human additives: Studies in vitro and in vivo
  18. Adult human bone marrow stromal spheres express neuronal traits in vitro and in a rat model of Parkinson's disease
  19. Tyrosine hydroxylase gene regulation in human neuronal progenitor cells does not depend on Nurr1 as in the murine and rat systems
  20. Purified mouse dopamine neurons thrive and function after transplantation into brain but require novel glial factors for survival in culture.
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