16D0 Lepore, Angelo - Thomas Jefferson University - Thomas Jefferson University

Angelo Lepore, PhD

Contact Dr. Lepore

900 Walnut St.
Suite 469
Philadelphia, PA 19107

(215) 503-5864
(215) 955-4949 fax

Most Recent Peer-reviewed Publications

  1. Persistent at-level thermal hyperalgesia and tactile allodynia accompany chronic neuronal and astrocyte activation in superficial dorsal horn following mouse cervical contusion spinal cord injury
  2. Immunohistochemical toolkit for tracking and quantifying xenotransplanted human stem cells
  3. Overexpression of the astrocyte glutamate transporter GLT1 exacerbates phrenic motor neuron degeneration, diaphragm compromise, and forelimb motor dysfunction following cervical contusion spinal cord injury
  4. Chronic at-level thermal hyperalgesia following rat cervical contusion spinal cord injury is accompanied by neuronal and astrocyte activation and loss of the astrocyte glutamate transporter, GLT1, in superficial dorsal horn
  5. Early phrenic motor neuron loss and transient respiratory abnormalities after unilateral cervical spinal cord contusion
  6. Degeneration of phrenic motor neurons induces long-term diaphragm deficits following mid-cervical spinal contusion in mice
  7. Phrenic motor neuron degeneration compromises phrenic axonal circuitry and diaphragm activity in a unilateral cervical contusion model of spinal cord injury
  8. Reduction in expression of the astrocyte glutamate tr 13BF ansporter, GLT1, worsens functional and histological outcomes following traumatic spinal cord injury
  9. Astrocytes carrying the superoxide dismutase 1 (SOD1 G93A) mutation induce wild-type motor neuron degeneration in vivo
  10. Stem cell transplantation for spinal cord neurodegeneration
  11. Human Glial-restricted progenitor transplantation into cervical spinal cord of the SOD1 G93A mouse model of ALS
  12. Intraspinal cell transplantation for targeting cervical ventral horn in amyotrophic lateral sclerosis and traumatic spinal cord injury
  13. Spatial and temporal changes in promoter activity of the astrocyte glutamate transporter GLT1 following traumatic spinal cord injury
  14. Peripheral hyperstimulation alters site of disease onset and course in SOD1 rats
  15. Presynaptic Regulation of Astroglial Excitatory Neurotransmitter Transporter GLT1
  16. Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease
  17. Selective ablation of proliferating astrocytes does not affect disease outcome in either acute or chronic models of motor neuron degeneration
  18. Adult glial precursor proliferation in mutant SOD1G93A mice
  19. Intraparenchymal spinal cord delivery of adeno-associated virus IGF-1 is protective in the SOD1G93A model of ALS
  20. Targeted stem cell transplantation strategies in ALS