Angelo Lepore, PhD

Contact Dr. Lepore

900 Walnut Street
JHN 4th floor
Philadelphia, PA 19107

(215) 503-5864
(215) 503-4358 fax

Most Recent Peer-reviewed Publications

  1. Mutation of the caspase-3 cleavage site in the astroglial glutamate transporter EAAT2 delays disease progression and extends lifespan in the SOD1-G93A mouse model of ALS
  2. Improving the therapeutic efficacy of neural progenitor cell transplantation following spinal cord injury
  3. MAP7 regulates axon collateral branch development in dorsal root ganglion neurons
  4. Harnessing the power of cell transplantation to target respiratory dysfunction following spinal cord injury
  5. Corticothalamic network dysfunction and behavioral deficits in a mouse model of Alzheimer's disease
  6. iPS cell transplantation for traumatic spinal cord injury
  7. GLT1 overexpression reverses established neuropathic pain-related behavior and attenuates chronic dorsal horn neuron activation following cervical spinal cord injury
  8. GLT1 overexpression in SOD1G93A mouse cervical spinal cord does not preserve diaphragm function or extend disease
  9. Functional and morphological assessment of diaphragm innervation by phrenic motor neurons
  10. Kv3.4 channel function and dysfunction in nociceptors
  11. Therapeutically targeting astrocytes with stem and progenitor cell transplantation following traumatic spinal cord injury
  12. Dysregulation of Kv3.4 channels in dorsal root ganglia following spinal cord injury
  13. Transplantation of glial progenitors that overexpress glutamate transporter GLT1 preserves diaphragm function following cervical SCI
  14. Human iPS cell-derived astrocyte transplants preserve respiratory function after spinal cord injury
  15. Persistent at-level thermal hyperalgesia and tactile allodynia accompany chronic neuronal and astrocyte activation in superficial dorsal horn following mouse cervical contusion spinal cord injury
  16. Chronic at-level thermal hyperalgesia following rat cervical contusion spinal cord injury is accompanied by neuronal and astrocyte activation and loss of the astrocyte glutamate transporter, GLT1, in superficial dorsal horn
  17. Immunohistochemical toolkit for tracking and quantifying xenotransplanted human stem cells
  18. Overexpression of the astrocyte glutamate transporter GLT1 exacerbates phrenic motor neuron degeneration, diaphragm compromise, and forelimb motor dysfunction following cervical contusion spinal cord injury
  19. Early phrenic motor neuron loss and transient respiratory abnormalities after unilateral cervical spinal cord contusion
  20. Degeneration of phrenic motor neurons induces long-term diaphragm deficits following mid-cervical spinal contusion in mice