2A1C Lepore, Angelo - Thomas Jefferson University - Thomas Jefferson University
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Angelo Lepore, PhD

Contact Dr. Lepore

900 Walnut St.
Suite 469
Philadelphia, PA 19107

(215) 503-5864
(215) 955-4949 fax

Most Recent Peer-reviewed Publications

  1. Overexpression of the astrocyte glutamate transporter GLT1 exacerbates phrenic motor neuron degeneration, diaphragm compromise, and forelimb motor dysfunction following cervical contusion spinal cord injury
  2. Early phrenic motor neuron loss and transient respiratory abnormalities after unilateral cervical spinal cord contusion
  3. Degeneration of phrenic motor neurons induces long-term diaphragm deficits following mid-cervical spinal contusion in mice
  4. Phrenic motor neuron degeneration compromises phrenic axonal circuitry and diaphragm activity in a unilateral cervical contusion model of spinal cord injury
  5. Reduction in expression of the astrocyte glutamate transporter, GLT1, worsens functional and histological outcomes following traumatic spinal cord injury
  6. Intraspinal cell transplantation for targeting cervical ventral horn in amyotrophic lateral sclerosis and traumatic spinal cord injury.
  7. Astrocytes carrying the superoxide dismutase 1 (SOD1 G93A) mutation induce wild-type motor neuron degeneration in vivo
  8. Stem cell transplantation for spinal cord neurodegeneration
  9. Human Glial-restricted progenitor transplantation into cervical spinal cord of the SOD1 G93A mouse model of ALS
  10. Intraspinal cell transplantation for targeting cervical ventral horn in amyotrophic lateral sclerosis and traumatic spinal cord injury
  11. Spatial and temporal changes in promoter activity of the astrocyte glutamate transporter GLT1 following traumatic spinal cord injury
  12. Transplantation of human glial restricted progenitors and derived astrocytes into a contusion model of spinal cord injury
  13. Peripheral hyperstimulation alters site of disease onset and course in SOD1 rats
  14. Presynaptic Regulation of Astroglial Excitatory Neurotransmitter Transporter GLT1
  15. Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease
  16. Selective ablation of proliferating astrocytes does not affect disease outcome in either acute or chronic models of motor neuron degeneration
  17. Adult glial precursor proliferation in mutant SOD1G93A mice
  18. Intraparenchymal spinal cord delivery of adeno-associated virus IGF-1 is protective in the SOD1G93A model of ALS
  19. Targeted stem cell transplantation strategies in ALS
  20. Long-term fate of neural precursor cells following transplantation into developing and adult CNS (DOI:10.1016/j.neuroscience.2005.12.043)
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