Thomas Jefferson UniversitySidney Kimmel Medical College

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Corticotropin-Releasing Factor (CRF)-serotonin (5-HT) Interactions

Rita Valentino, PhD

Rita Valentino, PhD
Children's Hospital of Philadelphia
Principal Investigator
(NIH/NIDA)

Elisabeth J. Van Bockstaele, PhD

Elisabeth J. Van Bockstaele, PhD
Co-Investigator

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Maria Waselus
Graduate Student
Molecular Cell Biology Program

CRF and vGlut1 in the dorsolateral DRNCRF and vGlut1 in the dorsolateral DRN

Goal: To examine interactions between the stress hormone CRF and serotonin (5-HT) in the dorsal raphe nucleus (DRN). Ultrastructural studies examining CRF afferents and their post-synaptic targets in DRN subregions are intended to elucidate the anatomical substrates involved in the regulation of the DRN-5-HT system by CRF.

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