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Motomi Enotomi-Iwamoto, PhD, DDS

Contact Dr. Enotomi-Iwamoto

Children's Hospital of Philadelphia
3400 Civic Center Blvd,
Philadelphia, PA 19104


Most Recent Peer-reviewed Publications

  1. Cell origin, volume and arrangement are drivers of articular cartilage formation, morphogenesis and response to injury in mouse limbs
  2. Genetic and pharmacological inhibition of retinoic acid receptor γ function promotes endochondral bone formation
  3. Cell therapy for the degenerating intervertebral disc
  4. Nanoindentation modulus of murine cartilage: a sensitive indicator of the initiation and progression of post-traumatic osteoarthritis
  5. EGFR signaling is critical for maintaining the superficial layer of articular cartilage and preventing osteoarthritis initiation
  6. Intervertebral disc development and disease-related genetic polymorphisms
  7. Alpha 5 integrin mediates osteoarthritic changes in mouse knee joints
  8. Tendon mineralization is progressive and associated with deterioration of tendon biomechanical properties, and requires BMP-Smad signaling in the mouse Achilles tendon injury model
  9. Wnt signaling in cartilage development and diseases: Lessons from animal studies
  10. Articular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg
  11. IL-1β irreversibly inhibits tenogenic differentiation and alters metabolism in injured tendon-derived progenitor cells in vitro
  12. Heparanase stimulates chondrogenesis and is up-regulated in human ectopic cartilage: A mechanism possibly involved in hereditary multiple exostoses
  13. The type 2 diabetes associated rs7903146 T allele within TCF7L2 is significantly under-represented in Hereditary Multiple Exostoses: Insights into pathogenesis
  14. Mouse limb skeletal growth and synovial joint development are coordinately enhanced by Kartogenin
  15. Resident mesenchymal progenitors of articular cartilage
  16. Reduced EGFR signaling enhances cartilage destruction in a mouse osteoarthritis model
  17. Distribution of slow-cycling cells in epiphyseal cartilage and requirement of β-catenin signaling for their maintenance in growth plate
  18. Tendon progenitor cells in injured tendons have strong chondrogenic potential: The cd105-negative subpopulation induces chondrogenic degeneration
  19. Epidermal growth factor receptor (EGFR) signaling regulates epiphyseal cartilage development through β-catenin-dependent and -independent pathways
  20. Epiphyseal abnormalities, trabecular bone loss and articular chondrocyte hypertrophy develop in the long bones of postnatal Ext1-deficient mice