111C Markova, Dessislava - Thomas Jefferson University - Thomas Jefferson University

Dessislava Markova, PhD

Contact Dr. Markova

1015 Walnut Street
Curtis Building, Suite 501
Philadelphia, PA 19107

(215) 955-7655
(215) 955-9773 fax

Most Recent Peer-reviewed Publications

  1. Substance p receptor antagonist suppresses inflammatory cytokine expression in human disc cells
  2. Aquaporin 1 and 5 expression decreases during human intervertebral disc degeneration: Novel HIF-1-mediated regulation of aquaporins in NP cells
  3. Fibronectin splice variation in human knee cartilage, meniscus and synovial membrane: Observations in osteoarthritic knee
  4. FIH-1-Mint3 axis does not control HIF-1α transcriptional activity in nucleus pulposus cells
  5. Fibronectin fragments and the cleaving enzyme ADAM-8 in the degenerative human intervertebral dis 1A04 c
  6. CCN2 suppresses catabolic effects of interleukin-1β through α5β1 and αVβ3 Integrins in nucleus pulposus cells: Implications in intervertebral disc degeneration
  7. Xylosyltransferase-1 expression is refractory to inhibition by the inflammatory cytokines tumor necrosis factor α and IL-1β in nucleus pulposus cells: Novel regulation by AP-1, Sp1, and Sp3
  8. Substance p stimulates production of inflammatory cytokines in human disc cells
  9. An organ culture system to model early degenerative changes of the intervertebral disc II: Profiling global gene expression changes
  10. COL6A3 protein deficiency in mice leads to muscle and tendon defects similar to human collagen VI congenital muscular dystrophy
  11. Expression and relationship of proinflammatory chemokine RANTES/CCL5 and cytokine IL-1 β in painful human intervertebral discs
  12. Human umbilical cord blood-derived mesenchymal stem cells in the cultured rabbit intervertebral disc: A novel cell source for disc repair
  13. Expression of Prolyl Hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: Distinct roles of PHD2 and PHD3 proteins in controlling HIF-1α activity in hypoxia
  14. Loss of fibulin-2 protects against progressive ventricular dysfunction after myocardial infarction
  15. TNF-α and IL-1β promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc
  16. An organ culture system to model early degenerative changes of the intervertebral disc
  17. Histological features of the degenerating intervertebral disc in a goat disc-injury model
  18. Hypoxia activates the notch signaling pathway in cells of the intervertebral disc: Implications in degenerative disc disease
  19. Fibronectin splicing variants in human intervertebral disc and association with disc degeneration
  20. Regulation of CCN2/connective tissue growth factor expression in the nucleus pulposus of the intervertebral disc: Role of smad and activator protein 1 signaling