0B68 Risbud, Makarand V. - Thomas Jefferson University - Thomas Jefferson University
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Makarand V. Risbud, PhD

Contact Dr. Risbud

1015 Walnut Street
Suite 501, Curtis Bldg.
Philadelphia, PA 19107


Most Recent Peer-reviewed Publications

  1. CCN2 suppresses catabolic effects of interleukin-1β through α5β1 and αVβ3 Integrins in nucleus pulposus cells: Implications in intervertebral disc degeneration
  2. HIF-1-PHD2 axis controls expression of syndecan 4 in nucleus pulposus cells
  3. Role of cytokines in intervertebral disc degeneration: Pain and disc content
  4. Substance p stimulates production of inflammatory cytokines in human disc cells
  5. An organ culture system to model early degenerative changes of the intervertebral disc II: Profiling global gene expression changes
  6. Molecular regulation of CCN2 in the intervertebral disc: Lessons learned from other connective tissues
  7. Inflammatory cytokines induce NOTCH signaling in nucleus pulposus cells: Implications in intervertebral disc degeneration
  8. Inflammatory cytokines associated with degenerative disc disease control aggrecanase-1 (ADAMTS-4) expression in nucleus pulposus cells through MAPK and NF-κB
  9. Expression and relationship of proinflammatory chemokine RANTES/CCL5 and cytokine IL-1 β in painful human intervertebral discs
  10. Hypoxia-inducible factor (HIF)-1α and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1α level and transcriptional activity
  11. The molecular basis of intervertebral disc degeneration
  12. Tumor necrosis factor α- And interleukin-1β-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1
  13. Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc
  14. Prolyl hydroxylase 3 (PHD3) modulates catabolic effects of tumor necrosis factor-α (TNF-α) on cells of the nucleus pulposus through co-activation of nuclear factor κB (NF-κB)/p65 signaling
  15. Smad3 controls β-1,3-glucuronosyltransferase 1 expression in rat nucleus pulposus cells: Implications of dysregulated expression in disc disease
  16. Expression of Prolyl Hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: Distinct roles of PHD2 and PHD3 proteins in controlling HIF-1α activity in hypoxia
  17. Tonicity enhancer binding protein (TonEBP) and hypoxia-inducible factor (HIF) coordinate heat shock protein 70 (Hsp70) expression in hypoxic nucleus pulposus cells: Role of Hsp70 in HIF-1α degradation
  18. Is the spinal motion segment a diarthrodial polyaxial joint: What a nice nucleus like you doing in a joint like this?
  19. Reply
  20. HIF-1α and HIF-2α degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc
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