mvr001

Makarand V. Risbud, PhD

Contact Dr. Risbud

1015 Walnut Street
Suite 501, Curtis Bldg.
Philadelphia, PA 19107


Most Recent Peer-reviewed Publications

  1. New horizons in spine research: Intervertebral disc repair and regeneration
  2. RNA sequencing reveals a role of TonEBP transcription factor in regulation of pro-inflammatory genes in response to hyperosmolarity in healthy nucleus pulposus cells a homeostatic response?
  3. Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling
  4. New Horizons in Spine Research: Disc biology, spine biomechanics and pathomechanisms of back pain
  5. Molecular mechanisms of biological aging in intervertebral discs
  6. N-cadherin is key to expression of the nucleus pulposus cell phenotype under selective substrate culture conditions
  7. Class i and IIa HDACs Mediate HIF-1α Stability Through PHD2-Dependent Mechanism, while HDAC6, a Class IIb Member, Promotes HIF-1α Transcriptional Activity in Nucleus Pulposus Cells of the Intervertebral Disc
  8. Syndecan-4 in intervertebral disc and cartilage: Saint or synner?
  9. The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells
  10. Circadian factors BMAL1 and RORα control HIF-1α transcriptional activity in nucleus pulposus cells: Implications in maintenance of intervertebral disc health
  11. TGFβ regulates Galectin-3 expression through canonical Smad3 signaling pathway in nucleus pulposus cells: Implications in intervertebral disc degeneration
  12. Matrix vesicles: Are they anchored exosomes?
  13. Prolyl-4-hydroxylase domain protein 2 controls NF-κB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus
  14. Discovery of the drivers of inflammation induced chronic low back pain: From bacteria to diabetes
  15. Understanding nucleus pulposus cell phenotype: A prerequisite for stem cell based therapies to treat intervertebral disc degeneration
  16. Disc in flames: Roles of TNF-α and IL-1β in intervertebral disc degeneration
  17. Defining the phenotype of young healthy nucleus pulposus cells: Recommendations of the spine research interest group at the 2014 annual ORS meeting
  18. Substance p receptor antagonist suppresses inflammatory cytokine expression in human disc cells
  19. Aquaporin 1 and 5 expression decreases during human intervertebral disc degeneration: Novel HIF-1-mediated regulation of aquaporins in NP cells
  20. Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus