111C Risbud, Makarand V. - Thomas Jefferson University - Thomas Jefferson University
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Makarand V. Risbud, PhD

Contact Dr. Risbud

1015 Walnut Street
Suite 501, Curtis Bldg.
Philadelphia, PA 19107


Most Recent Peer-reviewed Publications

  1. Prolyl-4-hydroxylase domain protein 2 controls NF-κB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus
  2. Defining the phenotype of young healthy nucleus pulposus cells: Recommendations of the spine research interest group at the 2014 annual ORS meeting
  3. Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus
  4. FIH-1-Mint3 axis does not control HIF-1α transcriptional activity in nucleus pulposus cells
  5. CCN2 suppresses catabolic effects of interleukin-1β through α5β1 and 111C Vβ3 Integrins in nucleus pulposus cells: Implications in intervertebral disc degeneration
  6. HIF-1-PHD2 axis controls expression of syndecan 4 in nucleus pulposus cells
  7. Tumor necrosis factor-α- and interleukin-1β-dependent matrix metalloproteinase-3 expression in nucleus pulposus cells requires cooperative signaling via syndecan 4 and mitogen-activated protein kinase-NF-κB axis: Implications in inflammatory disc disease
  8. Role of cytokines in intervertebral disc degeneration: Pain and disc content
  9. Extracellular osmolarity regulates matrix homeostasis in the intervertebral disc and articular cartilage: Evolving role of TonEBP
  10. Xylosyltransferase-1 expression is refractory to inhibition by the inflammatory cytokines tumor necrosis factor α and IL-1β in nucleus pulposus cells: Novel regulation by AP-1, Sp1, and Sp3
  11. Substance p stimulates production of inflammatory cytokines in human disc cells
  12. An organ culture system to model early degenerative changes of the intervertebral disc II: Profiling global gene expression changes
  13. Molecular regulation of CCN2 in the intervertebral disc: Lessons learned from other connective tissues
  14. Inflammatory cytokines induce NOTCH signaling in nucleus pulposus cells: Implications in intervertebral disc degeneration
  15. Inflammatory cytokines associated with degenerative disc disease control aggrecanase-1 (ADAMTS-4) expression in nucleus pulposus cells through MAPK and NF-κB
  16. Expression and relationship of proinflammatory chemokine RANTES/CCL5 and cytokine IL-1 β in painful human intervertebral discs
  17. Hypoxia-inducible factor (HIF)-1α and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1α level and transcriptional activity
  18. The molecular basis of intervertebral disc degeneration
  19. Tumor necrosis factor α- And interleukin-1β-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1
  20. Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc
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