27EC Risbud, Makarand V. - Thomas Jefferson University - Thomas Jefferson University
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Makarand V. Risbud, PhD

Contact Dr. Risbud

1015 Walnut Street
Suite 501, Curtis Bldg.
Philadelphia, PA 19107


Most Recent Peer-reviewed Publications

  1. Matrix vesicles: Are they anchored exosomes?
  2. Prolyl-4-hydroxylase domain protein 2 controls NF-κB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus
  3. Aquaporin 1 and 5 expression decreases during human intervertebral disc degeneration: Novel HIF-1-mediated regulation of aquaporins in NP cells
  4. Understanding nucleus pulposus cell phenotype: A prerequisite for stem cell based therapies to treat intervertebral disc degeneration
  5. Defining the phenotype of young healthy nucleus pulposus cells: Recommendations of the spine research interest group at the 2014 annual ORS meeting
  6. Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus
  7. FIH-1-Mint3 axis does not control HIF-1α transcriptional activity in nucleus pulposus cells
  8. CCN2 suppresses catabolic effects of interleukin-1β through α5β1 and αVβ3 Integrins in nucleus pulposus cells: Implications in intervertebral disc degeneration
  9. Microenvironmental control of disc cell function: Influence of hypoxia and osmotic pressure
  10. HIF-1-PHD2 axis controls expression of syndecan 4 in nucleus pulposus cells
  11. The intervertebral disc: Molecular and structural studies of the disc in health and disease
  12. Introduction to the structure, function, and comparative anatomy of the vertebrae and the intervertebral disc
  13. Tumor necrosis factor-α- and interleukin-1β-dependent matrix metalloproteinase-3 expression in nucleus pulposus cells requires cooperative signaling via syndecan 4 and mitogen-activated protein kinase-NF-κB axis: Implications in inflammatory disc disease
  14. Introduction
  15. Role of cytokines in intervertebral disc degeneration: Pain and disc content
  16. Extracellular osmolarity regulates matrix homeostasis in the intervertebral disc and articular cartilage: Evolving role of TonEBP
  17. Xylosyltransferase-1 expression is refractory to inhibition by the inflammatory cytokines tumor necrosis factor α and IL-1β in nucleus pulposus cells: Novel regulation by AP-1, Sp1, and Sp3
  18. Substance p stimulates production of inflammatory cytokines in human disc cells
  19. An organ culture system to model early degenerative changes of the intervertebral disc II: Profiling global gene expression changes
  20. Molecular regulation of CCN2 in the intervertebral disc: Lessons learned from other connective tissues
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