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Irving M. Shapiro, BDS, PhD

Contact Dr. Shapiro

1015 Walnut Street
Curtis Building, Suite 501
Philadelphia, PA 19107

(215) 955-7217
(215) 955-9159 fax

Most Recent Peer-reviewed Publications

  1. RNA sequencing reveals a role of TonEBP transcription factor in regulation of pro-inflammatory genes in response to hyperosmolarity in healthy nucleus pulposus cells a homeostatic response?
  2. Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling
  3. Syndecan-4 in intervertebral disc and cartilage: Saint or synner?
  4. Matrix vesicles: Are they anchored exosomes?
  5. Porphyrin-adsorbed Allograft Bone: A Photoactive, Antibiofilm Surface
  6. eNOS transfection of adipose-derived stem cells yields bioactive nitric oxide production and improved results in vascular tissue engineering
  7. Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus
  8. FIH-1-Mint3 axis does not control HIF-1α transcriptional activity in nucleus pulposus cells
  9. CCN2 suppresses catabolic effects of interleukin-1β through α5β1 and αVβ3 Integrins in nucleus pulposus cells: Implications in intervertebral disc degeneration
  10. Prosthesis Selection
  11. Microenvironmental control of disc cell function: Influence of hypoxia and osmotic pressure
  12. Introduction to the structure, function, and comparative anatomy of the vertebrae and the intervertebral disc
  13. The intervertebral disc: Molecular and structural studies of the disc in health and disease
  14. Role of cytokines in intervertebral disc degeneration: Pain and disc content
  15. Extracellular osmolarity regulates matrix homeostasis in the intervertebral disc and articular cartilage: Evolving role of TonEBP
  16. Boning up on autophagy :The role of autophagy in skeletal biology
  17. Tumor necrosis factor-α- and interleukin-1β-dependent matrix metalloproteinase-3 expression in nucleus pulposus cells requires cooperative signaling via syndecan 4 and mitogen-activated protein kinase-NF-κB axis: Implications in inflammatory disc disease
  18. Xylosyltransferase-1 expression is refractory to inhibition by the inflammatory cytokines tumor necrosis factor α and IL-1β in nucleus pulposus cells: Novel regulation by AP-1, Sp1, and Sp3
  19. HIF-1-PHD2 axis controls expression of syndecan 4 in nucleus pulposus cells
  20. Prosthesis selection