27EC Shapiro, Irving M. - Thomas Jefferson University - Thomas Jefferson University
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Irving M. Shapiro, BDS, PhD

Contact Dr. Shapiro

1015 Walnut Street
Curtis Building, Suite 501
Philadelphia, PA 19107

(215) 955-7217
(215) 955-9159 fax

Most Recent Peer-reviewed Publications

  1. Porphyrin-adsorbed Allograft Bone: A Photoactive, Antibiofilm Surface
  2. Staphylococcal persistence due to biofilm formation in synovial fluid containing prophylactic cefazolin
  3. Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus
  4. FIH-1-Mint3 axis does not control HIF-1α transcriptional activity in nucleus pulposus cells
  5. CCN2 suppresses catabolic effects of interleukin-1β through α5β1 and αVβ3 Integrins in nucleus pulposus cells: Implications in intervertebral disc degeneration
  6. Prosthesis Selection
  7. Prosthesis selection
  8. HIF-1-PHD2 axis controls expression of syndecan 4 in nucleus pulposus cells
  9. Boning up on autophagy :The role of autophagy in skeletal biology
  10. Tumor necrosis factor-α- and interleukin-1β-dependent matrix metalloproteinase-3 expression in nucleus pulposus cells requires cooperative signaling via syndecan 4 and mitogen-activated protein kinase-NF-κB axis: Implications in inflammatory disc disease
  11. Role of cytokines in intervertebral disc degeneration: Pain and disc content
  12. Extracellular osmolarity regulates matrix homeostasis in the intervertebral disc and articular cartilage: Evolving role of TonEBP
  13. Xylosyltransferase-1 expression is refractory to inhibition by the inflammatory cytokines tumor necrosis factor α and IL-1β in nucleus pulposus cells: Novel regulation by AP-1, Sp1, and Sp3
  14. An organ culture system to model early degenerative changes of the intervertebral disc II: Profiling global gene expression changes
  15. Molecular regulation of CCN2 in the intervertebral disc: Lessons learned from other connective tissues
  16. Inflammatory cytokines induce NOTCH signaling in nucleus pulposus cells: Implications in intervertebral disc degeneration
  17. Inflammatory cytokines associated with degenerative disc disease control aggrecanase-1 (ADAMTS-4) expression in nucleus pulposus cells through MAPK and NF-κB
  18. Hypoxia-inducible factor (HIF)-1α and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1α level and transcriptional activity
  19. Tumor necrosis factor α- And interleukin-1β-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1
  20. eNOS transfection of adipose-derived stem cells yields bioactive nitric oxide production and improved results in vascular tissue engineering
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