29AD Shapiro, Irving M. - Thomas Jefferson University - Thomas Jefferson University
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Irving M. Shapiro, BDS, PhD

Contact Dr. Shapiro

1015 Walnut Street
Curtis Building, Suite 501
Philadelphia, PA 19107

(215) 955-7217
(215) 955-9159 fax

Most Recent Peer-reviewed Publications

  1. Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling
  2. Syndecan-4 in intervertebral disc and cartilage: Saint or synner?
  3. Matrix vesicles: Are they anchored exosomes?
  4. Porphyrin-adsorbed Allograft Bone: A Photoactive, Antibiofilm Surface
  5. eNOS transfection of adipose-derived stem cells yields bioactive nitric oxide production and improved results in vascular tissue engineering
  6. Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus
  7. FIH-1-Mint3 axis does not control HIF-1α transcriptional activity in nucleus pulposus cells
  8. CCN2 suppresses catabolic effects of interleukin-1β through α5β1 and αVβ3 Integrins in nucleus pulposus cells: Implications in intervertebral disc degeneration
  9. Prosthesis Selection
  10. Role of cytokines in intervertebral disc degeneration: Pain and disc content
  11. Introduction to the structure, function, and comparative anatomy of the vertebrae and the intervertebral disc
  12. Microenvironmental control of disc cell function: Influence of hypoxia and osmotic pressure
  13. The intervertebral disc: Molecular and structural studies of the disc in health and disease
  14. Extracellular osmolarity regulates matrix homeostasis in the intervertebral disc and articular cartilage: Evolving role of TonEBP
  15. Boning up on autophagy :The role of autophagy in skeletal biology
  16. Tumor necrosis factor-α- and interleukin-1β-dependent matrix metalloproteinase-3 expression in nucleus pulposus cells requires cooperative signaling via syndecan 4 and mitogen-activated protein kinase-NF-κB axis: Implications in inflammatory disc disease
  17. HIF-1-PHD2 axis controls expression of syndecan 4 in nucleus pulposus cells
  18. Xylosyltransferase-1 expression is refractory to inhibition by the inflammatory cytokines tumor necrosis factor α and IL-1β in nucleus pulposus cells: Novel regulation by AP-1, Sp1, and Sp3
  19. Prosthesis selection
  20. An organ culture system to model early degenerative changes of the intervertebral disc II: Profiling global gene expression changes
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