0B68 Shapiro, Irving M. - Thomas Jefferson University - Thomas Jefferson University

Irving M. Shapiro, BDS, PhD

Contact Dr. Shapiro

1015 Walnut Street
Curtis Building, Suite 501
Philadelphia, PA 19107

(215) 955-7217
(215) 955-9159 fax

Most Recent Peer-reviewed Publications

  1. Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A sig 1E59 naling
  2. Syndecan-4 in intervertebral disc and cartilage: Saint or synner?
  3. Matrix vesicles: Are they anchored exosomes?
  4. Porphyrin-adsorbed Allograft Bone: A Photoactive, Antibiofilm Surface
  5. eNOS transfection of adipose-derived stem cells yields bioactive nitric oxide production and improved results in vascular tissue engineering
  6. Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus
  7. FIH-1-Mint3 axis does not control HIF-1α transcriptional activity in nucleus pulposus cells
  8. CCN2 suppresses catabolic effects of interleukin-1β through α5β1 and αVβ3 Integrins in nucleus pulposus cells: Implications in intervertebral disc degeneration
  9. Prosthesis Selection
  10. The intervertebral disc: Molecular and structural studies of the disc in health and disease
  11. Microenvironmental control of disc cell function: Influence of hypoxia and osmotic pressure
  12. Role of cytokines in intervertebral disc degeneration: Pain and disc content
  13. Introduction to the structure, function, and comparative anatomy of the vertebrae and the intervertebral disc
  14. Extracellular osmolarity regulates matrix homeostasis in the intervertebral disc and articular cartilage: Evolving role of TonEBP
  15. Boning up on autophagy :The role of autophagy in skeletal biology
  16. Tumor necrosis factor-α- and interleukin-1β-dependent matrix metalloproteinase-3 expression in nucleus pulposus cells requires cooperative signaling via syndecan 4 and mitogen-activated protein kinase-NF-κB axis: Implications in inflammatory disc disease
  17. Xylosyltransferase-1 expression is refractory to inhibition by the inflammatory cytokines tumor necrosis factor α and IL-1β in nucleus pulposus cells: Novel regulation by AP-1, Sp1, and Sp3
  18. HIF-1-PHD2 axis controls expression of syndecan 4 in nucleus pulposus cells
  19. Prosthesis selection
  20. An organ culture system to model early degenerative changes of the intervertebral disc II: Profiling global gene expression changes