Eric Londin, PhD

Eric Londin, PhD

Contact Dr. Londin

1020 Locust Street
JAH - M81
Philadelphia, PA 19107

(215) 503-0454
(215) 503-0466 fax

Most Recent Peer-reviewed Publications

  1. Posttranscriptional regulation of PARG mRNA by HuR facilitates DNA repair and resistance to PARP inhibitors
  2. Posttranscriptional upregulation of IDH1 by HuR establishes a powerful survival phenotype in pancreatic cancer cells
  3. Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma
  4. Threshold-seq: A tool for determining the threshold in short RNA-seq datasets
  5. CRISPR knockout of the HuR gene causes a xenograft lethal phenotype
  6. Recessive mutation in tetraspanin CD151 causes Kindler syndrome-like epidermolysis bullosa with multi-systemic manifestations including nephropathy
  7. Post-transcriptional regulation of BRCA2 through interactions with miR-19a and miR-19b
  8. GPRC5A is a potential oncogene in pancreatic ductal adenocarcinoma cells that is upregulated by gemcitabine with help from HuR
  9. Next generation sequencing in cancer: opportunities and challenges for precision cancer medicine
  10. High concentration capture probes enhance massively parallel sequencing assays
  11. The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells
  12. Knowledge about the presence or absence of miRNA isoforms (isomiRs) can successfully discriminate amongst 32 TCGA cancer types
  13. Beyond the one-locus-one-miRNA paradigm: microRNA isoforms enable deeper insights into breast cancer heterogeneity
  14. What is translational bioinformatics?
  15. Reply to Backes and Keller: Identification of novel tissue-specific and primate-specific human microRNAs
  16. Performance of exome sequencing for pharmacogenomics
  17. Clinical exome performance for reporting secondary genetic findings
  18. Argonaute CLIP-Seq reveals miRNA targetome diversity across tissue types
  19. HuR posttranscriptionally regulates WEE1: Implications for the DNA damage response in pancreatic cancer cells
  20. The human platelet: Strong transcriptome correlations among individuals associate weakly with the platelet proteome