0B68 Birbe, Ruth - Thomas Jefferson University - Thomas Jefferson University

Ruth Birbe, MD

Contact Dr. Birbe

132 S. 10th St.
Main Building, Suite 285A
Philadelphia, PA 19107

(215) 955-2494
(215) 923-1969 fax

Most Recent Peer-reviewed Publications

  1. Integrin avb6 Promotes an osteolytic program in cancer cells by upregulating MMP2
  2. USP22 regulates oncogenic signaling pathways to drive lethal cancer progression
  3. Oncogenes and inflammation rewire host energy metabolism in the tumor microenvironment RAS and NFκB target stromal MCT4
  4. Molecular diagnosis of prostate cancer: Are we up to age?
  5. The potential value of phosphohistone-H3 mitotic index determined by digital image analysis in the assessment of pancreatic endocrine tumors in fine-needle aspiration cytology specimens
  6. Convergence of oncogenic and hormone receptor pathways promotes metastatic phenotypes
  7. BRCA1 mutations drive oxidative stress and glycolysis in the tumor microenvironment: Implications for breast cancer prevention with antioxidant therapies
  8. Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis, via glycolysis and ketone production
  9. Does mitosis-specific marker phosphohistone H3 help the grading of upper tract urothelial carcinomas in cell blocks?
  10. Mitochondrial metabolism in cancer metastasis: Visualizing tumor cell mitochondria and the "reverse Warburg effect" in positive lymph node tissue
  11. Is cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism
  12. Pyruvate kinase expression (PKM1 and PKM2) in cancer associated fibroblasts drives stromal nutrient production and tumor growth
  13. Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: Visualizing the therapeutic effects of metformin in tumor tissue
  14. Matrix remodeling stimulates stromal autophagy, "fueling" cancer cell mitochondrial metabolism and metastasis
  15. Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts
  16. Lineage-specific T-cell responses to Cancer mucosa antigen oppose systemic metastases without mucosal inflammatory disease
  17. Guanylyl cyclase C-induced immunotherapeutic responses opposing tumor metastases without autoimmunity
  18. A validated quantitative assay to detect occult micrometastases by reverse transcriptase-polymerase chain reaction of guanylyl cyclase C in patients with colorectal cancer
  19. Bile Acids Induce Ectopic Expression of Intestinal Guanylyl Cyclase C Through Nuclear Factor-κB and Cdx2 in Human Esophageal Cells 02A2
  20. So-called inflammatory myofibroblastic tumour: A proliferative lesion of fibroblastic reticulum cells?