Jan B. Hoek, PhD

Jan B. Hoek, PhD

Contact Dr. Hoek

1020 Locust Street
Jefferson Alumni Hall, Suite 527
Philadelphia, PA 19107

(215) 503-5016
(215) 923-2218 fax

Most Recent Peer-reviewed Publications

  1. Mitochondrial Ca2+ and regulation of the permeability transition pore
  2. Computational Modeling of Spatiotemporal Ca2+ Signal Propagation Along Hepatocyte Cords
  3. Synergistic effects of ascorbate and sorafenib in hepatocellular carcinoma: New insights into ascorbate cytotoxicity
  4. MICU1 regulation of mitochondrial Ca 2+ uptake dictates survival and tissue regeneration
  5. Inhibition of miR-21 rescues liver regeneration after partial hepatectomy in ethanol-fed rats
  6. In vivo zonal variation and liver cell-type specific NF-κB localization after chronic adaptation to ethanol and following partial hepatectomy
  7. Multistrip western blotting: A tool for comparative quantitative analysis of multiple proteins
  8. Computational modeling analysis of mitochondrial superoxide production under varying substrate conditions and upon inhibition of different segments of the electron transport chain
  9. Silence on the relevant literature and errors in implementation
  10. Alcohol and breast cancer: Reconciling epidemiological and molecular data
  11. Preface
  12. Multistrip western blotting: A tool for comparative quantitative analysis of multiple proteins
  13. A novel, dynamic pattern-based analysis of NF-κB binding during the priming phase of liver regeneration reveals switch-like functional regulation of target genes
  14. Adiponectin fine-tuning of liver regeneration dynamics revealed through cellular network modelling
  15. Amygdalar neuronal plasticity and the interactions of alcohol, sex, and stress
  16. Pharmacological ceramide reduction alleviates alcohol-induced steatosis and hepatomegaly in adiponectin knockout mice
  17. Decorin induces mitophagy in breast carcinoma cells via peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) and mitostatin
  18. Computational analysis of hysteresis and bistability in the mitochondrial respiratory chain
  19. Computational modeling analysis of acute and chronic ethanol-induced oxidative stress
  20. Theoretical analysis of the epidermal growth factor receptor signaling network under the control condition and after chronic ethanol treatment