Jan B. Hoek, PhD

Jan B. Hoek, PhD

Contact Dr. Hoek

1020 Locust Street
Jefferson Alumni Hall, Suite 527
Philadelphia, PA 19107

(215) 503-5016
(215) 923-2218 fax

Most Recent Peer-reviewed Publications

  1. The path from mitochondrial ROS to aging runs through the mitochondrial permeability transition pore
  2. Alcohol-Mediated Missplicing of Mcl-1 Pre-mRNA is Involved in Neurotoxicity
  3. Biochemical effects of exercise on a fasciocutaneous flap in a rat model
  4. Chronic alcohol feeding potentiates hormone-induced calcium signalling in hepatocytes
  5. Mitochondrial Ca2+and regulation of the permeability transition pore
  6. Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity
  7. Pattern analysis uncovers a chronic ethanol-induced disruption of the switchlike dynamics of C/EBP-β and C/EBP-α genome-wide binding during liver regeneration
  8. Computational Modeling of Spatiotemporal Ca2+Signal Propagation Along Hepatocyte Cords
  9. Synergistic effects of ascorbate and sorafenib in hepatocellular carcinoma: New insights into ascorbate cytotoxicity
  10. Aging effects on pedicled fasciocutaneous flap survival in rats
  11. A novel comparative pattern analysis approach identifies chronic alcohol mediated dysregulation of transcriptomic dynamics during liver regeneration
  12. MICU1 regulation of mitochondrial Ca 2+ uptake dictates survival and tissue regeneration
  13. A novel comparative pattern count analysis reveals a chronic ethanol-induced dynamic shift in immediate early NF-κB genome-wide promoter binding during liver regeneration
  14. Inhibition of miR-21 rescues liver regeneration after partial hepatectomy in ethanol-fed rats
  15. Amygdalar neuronal plasticity and the interactions of alcohol, sex, and stress
  16. In vivo zonal variation and liver cell-type specific NF-κB localization after chronic adaptation to ethanol and following partial hepatectomy
  17. Multistrip western blotting: A tool for comparative quantitative analysis of multiple proteins
  18. Computational modeling analysis of mitochondrial superoxide production under varying substrate conditions and upon inhibition of different segments of the electron transport chain
  19. Silence on the relevant literature and errors in implementation
  20. Alcohol and breast cancer: Reconciling epidemiological and molecular data