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Isidore Rigoutsos, PhD

Contact Dr. Rigoutsos

1020 Locust Street
Room M81 Alumni Hall
Philadelphia, PA 19107

(215) 503-6152
(215) 503-0466 fax

Most Recent Peer-reviewed Publications

  1. Accurate profiling and quantification of tRNA fragments from RNA-Seq Data: A Vade Mecum for MINTmap
  2. Increasing cell density globally enhances the biogenesis of Piwi-interacting RNAs in Bombyx mori germ cells
  3. The biogenesis pathway of tRNA-derived piRNAs in Bombyx germ cells
  4. Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma
  5. An miRNA expression signature for the human colonic stem cell niche distinguishes malignant from normal epithelia
  6. Threshold-seq: A tool for determining the threshold in short RNA-seq datasets
  7. N-BLR, a primate-specific non-coding transcript leads to colorectal cancer invasion and migration
  8. YAMAT-seq: An efficient method for high-throughput sequencing of mature transfer RNAs
  9. MINTmap: Fast and exhaustive profiling of nuclear and mitochondrial tRNA fragments from short RNA-seq data
  10. Post-transcriptional regulation of BRCA2 through interactions with miR-19a and miR-19b
  11. MINTbase: A framework for the interactive exploration of mitochondrial and nuclear tRNA fragments
  12. GPRC5A is a potential oncogene in pancreatic ductal adenocarcinoma cells that is upregulated by gemcitabine with help from HuR
  13. Integrative Multi-omic Analysis of Human Platelet eQTLs Reveals Alternative Start Site in Mitofusin 2
  14. The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells
  15. Consequential considerations when mapping tRNA fragments
  16. Knowledge about the presence or absence of miRNA isoforms (isomiRs) can successfully discriminate amongst 32 TCGA cancer types
  17. Aging-associated changes in microRNA expression profile of internal anal sphincter smooth muscle: Role of microRNA-133a
  18. Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer
  19. Beyond the one-locus-one-miRNA paradigm: microRNA isoforms enable deeper insights into breast cancer heterogeneity
  20. Sex hormone-dependent tRNA halves enhance cell proliferation in breast and prostate cancers