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Isidore Rigoutsos, PhD

Contact Dr. Rigoutsos

1020 Locust Street
Room M81 Alumni Hall
Philadelphia, PA 19107

(215) 503-6152
(215) 503-0466 fax

Most Recent Peer-reviewed Publications

  1. N-BLR, a primate-specific non-coding transcript leads to colorectal cancer invasion and migration
  2. MINTmap: Fast and exhaustive profiling of nuclear and mitochondrial tRNA fragments from short RNA-seq data
  3. Post-transcriptional regulation of BRCA2 through interactions with miR-19a and miR-19b
  4. MINTbase: A framework for the interactive exploration of mitochondrial and nuclear tRNA fragments
  5. Integrative Multi-omic Analysis of Human Platelet eQTLs Reveals Alternative Start Site in Mitofusin 2
  6. The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells
  7. Consequential considerations when mapping tRNA fragments
  8. Aging-associated changes in microRNA expression profile of internal anal sphincter smooth muscle: Role of microRNA-133a
  9. Knowledge about the presence or absence of miRNA isoforms (isomiRs) can successfully discriminate amongst 32 TCGA cancer types
  10. Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer
  11. Beyond the one-locus-one-miRNA paradigm: microRNA isoforms enable deeper insights into breast cancer heterogeneity
  12. Sex hormone-dependent tRNA halves enhance cell proliferation in breast and prostate cancers
  13. Reply to Backes and Keller: Identification of novel tissue-specific and primate-specific human microRNAs
  14. Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- And tissue-specific microRNAs
  15. "Off-Spotter": Very fast and exhaustive enumeration of genomic lookalikes for designing CRISPR/Cas guide RNAs
  16. Post-transcriptional regulation of BRCA1 through its coding sequence by the miR-15/107 group of miRNAs
  17. Mitochondrial tRNA-lookalikes in nuclear chromosomes: Could they be functional?
  18. Dissecting tRNA-derived fragment complexities using personalized transcriptomes reveals novel fragment classes and unexpected dependencies
  19. Argonaute CLIP-Seq reveals miRNA targetome diversity across tissue types
  20. HuR posttranscriptionally regulates WEE1: Implications for the DNA damage response in pancreatic cancer cells