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Erin Seifert, PhD

Contact Dr. Seifert

1020 Locust Street
527A JAH
Philadelphia, PA 19107

(215) 503-5030

Most Recent Peer-reviewed Publications

  1. Posttranscriptional upregulation of IDH1 by HuR establishes a powerful survival phenotype in pancreatic cancer cells
  2. MSTO1 is a cytoplasmic pro-mitochondrial fusion protein, whose mutation induces myopathy and ataxia in humans
  3. Cyclin D1 restrains oncogene-induced autophagy by regulating the AMPK–LKB1 signaling axis
  4. Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca2+ Signals Is Controlled by the Stoichiometry of MICU1/2 and MCU
  5. TP53-inducible glycolysis and apoptosis regulator (TIGAR) metabolically reprograms carcinoma and stromal cells in breast cancer
  6. Natural and induced mitochondrial phosphate carrier loss: Differential dependence of mitochondrial metabolism and dynamics and cell survival on the extent of depletion
  7. Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling
  8. MICU1 regulation of mitochondrial Ca 2+ uptake dictates survival and tissue regeneration
  9. Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress
  10. The mitochondrial phosphate carrier: Role in oxidative metabolism, calcium handling and mitochondrial disease
  11. IL-15Rα is a determinant of muscle fuel utilization, and its loss protects against obesity
  12. Acyl-CoA thioesterase-2 facilitates mitochondrial fatty acid oxidation in the liver
  13. Lower mitochondrial proton leak and decreased glutathione redox in primary muscle cells of obese diet-resistant versus diet-sensitive humans
  14. The retinal pigment epithelium utilizes fatty acids for ketogenesis implications for metabolic coupling with the outer retina
  15. Functional Mitochondrial analysis in acute brain sections from adult rats reveals mitochondrial dysfunction in a rat model of Migraine
  16. The SIRT1 deacetylase protects mice against the symptoms of metabolic syndrome
  17. Reliance of ER-mitochondrial calcium signaling on mitochondrial EF-hand Ca2+ binding proteins: Miros, MICUs, LETM1 and solute carriers
  18. Erratum: Muscle uncoupling protein 3 overexpression mimics endurance training and reduces circulating biomarkers of incomplete β-oxidation (FASEB Journal (2013) 27 (4213- 4225) DOI: 10.1096/fj.13-234302)
  19. Muscle uncoupling protein 3 overexpression mimics endurance training and reduces circulating biomarkers of incomplete β-oxidation
  20. MICU1 controls both the threshold and cooperative activation of the mitochondrial Ca2+ uniporter