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Erin Seifert, PhD

Contact Dr. Seifert

1020 Locust Street
527A JAH
Philadelphia, PA 19107

(215) 503-5030

Most Recent Peer-reviewed Publications

  1. Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca2+ Signals Is Controlled by the Stoichiometry of MICU1/2 and MCU
  2. MSTO1 is a cytoplasmic pro-mitochondrial fusion protein, whose mutation induces myopathy and ataxia in humans
  3. Natural and induced mitochondrial phosphate carrier loss: Differential dependence of mitochondrial metabolism and dynamics and cell survival on the extent of depletion
  4. Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling
  5. MICU1 regulation of mitochondrial Ca 2+ uptake dictates survival and tissue regeneration
  6. Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress
  7. The mitochondrial phosphate carrier: Role in oxidative metabolism, calcium handling and mitochondrial disease
  8. IL-15Rα is a determinant of muscle fuel utilization, and its loss protects against obesity
  9. Acyl-CoA thioesterase-2 facilitates mitochondrial fatty acid oxidation in the liver
  10. Lower mitochondrial proton leak and decreased glutathione redox in primary muscle cells of obese diet-resistant versus diet-sensitive humans
  11. The retinal pigment epithelium utilizes fatty acids for ketogenesis implications for metabolic coupling with the outer retina
  12. Functional Mitochondrial analysis in acute brain sections from adult rats reveals mitochondrial dysfunction in a rat model of Migraine
  13. Reliance of ER-mitochondrial calcium signaling on mitochondrial EF-hand Ca2+ binding proteins: Miros, MICUs, LETM1 and solute carriers
  14. The SIRT1 deacetylase protects mice against the symptoms of metabolic syndrome
  15. Erratum: Muscle uncoupling protein 3 overexpression mimics endurance training and reduces circulating biomarkers of incomplete β-oxidation (FASEB Journal (2013) 27 (4213- 4225) DOI: 10.1096/fj.13-234302)
  16. Muscle uncoupling protein 3 overexpression mimics endurance training and reduces circulating biomarkers of incomplete β-oxidation
  17. MICU1 controls both the threshold and cooperative activation of the mitochondrial Ca2+ uniporter
  18. Intrinsic aerobic capacity correlates with greater inherent mitochondrial oxidative and H2O2 emission capacities without major shifts in myosin heavy chain isoform
  19. Calorie restriction in mice overexpressing UCP3: Evidence that prior mitochondrial uncoupling alters response
  20. SirT1 catalytic activity is required for male fertility and metabolic homeostasis in mice