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Haifeng Yang, PhD

Contact Dr. Yang

1020 Locust Street
JAH 336D
Philadelphia, PA 19107

(215) 503-6163

Most Recent Peer-reviewed Publications

  1. Intratumoral heterogeneity analysis reveals hidden associations between protein expression losses and patient survival in clear cell renal cell carcinoma
  2. Immunohistochemistry successfully uncovers intratumoral heterogeneity and widespread co-losses of chromatin regulators in clear cell renal cell carcinoma
  3. The structure and regulation of Cullin 2 based E3 ubiquitin ligases and their biological functions
  4. The roles of chromatin-remodelers and epigenetic modifiers in kidney cancer
  5. The contributions of HIF-target genes to tumor growth in RCC
  6. The roles of VHL-dependent ubiquitination in signaling and cancer
  7. The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C
  8. The von hippel-lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR
  9. pVHL Acts as an Adaptor to Promote the Inhibitory Phosphorylation of the NF-κB Agonist Card9 by CK2
  10. Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: Developmental culling and cancer
  11. Analysis of von Hippel-Lindau Hereditary Cancer Syndrome: Implications of Oxygen Sensing
  12. Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
  13. Structure of an HIF-1α-pVHL complex: Hydroxyproline recognition in signaling
  14. Molecular pathogenesis of the von Hippel-Lindau hereditary cancer syndrome: Implications for oxygen sensing
  15. Von Hippel-Lindau protein mutants linked to type 2C VHL disease preserve the ability to downregulate HIF
  16. HIFα targeted for VHL-mediated destruction by proline hydroxylation: Implications for O2 sensing
  17. Loss of a protein phosphatase 2A regulatory subunit (Cdc55p) elicits improper regulation of Swe1p degradation
  18. Variation among cell types in the signaling pathways by which IGF-I stimulates specific cellular responses
  19. Molecular genetic analysis of Rts1p, a B' regulatory subunit of Saccharomyces cerevisiae protein phosphatase 2A