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Haifeng Yang, PhD

Contact Dr. Yang

1020 Locust Street
JAH 336D
Philadelphia, PA 19107

(215) 503-6163

Most Recent Peer-reviewed Publications

  1. Immunohistochemistry successfully uncovers intratumoral heterogeneity and widespread co-losses of chromatin regulators in clear cell renal cell carcinoma
  2. The structure and regulation of Cullin 2 based E3 ubiquitin ligases and their biological functions
  3. The roles of chromatin-remodelers and epigenetic modifiers in kidney cancer
  4. The contributions of HIF-target genes to tumor growth in RCC
  5. The roles of VHL-dependent ubiquitination in signaling and cancer
  6. The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C
  7. The von hippel-lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR
  8. pVHL Acts as an Adaptor to Promote the Inhibitory Phosphorylation of the NF-κB Agonist Card9 by CK2
  9. Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: Developmental culling and cancer
  10. Analysis of von Hippel-Lindau Hereditary Cancer Syndrome: Implications of Oxygen Sensing
  11. Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
  12. Structure of an HIF-1α-pVHL complex: Hydroxyproline recognition in signaling
  13. Molecular pathogenesis of the von Hippel-Lindau hereditary cancer syndrome: Implications for oxygen sensing
  14. Von Hippel-Lindau protein mutants linked to type 2C VHL disease preserve the ability to downregulate HIF
  15. HIFα targeted for VHL-mediated destruction by proline hydroxylation: Implications for O2 sensing
  16. Loss of a protein phosphatase 2A regulatory subunit (Cdc55p) elicits improper regulation of Swe1p degradation
  17. Variation among cell types in the signaling pathways by which IGF-I stimulates specific cellular responses
  18. Molecular genetic analysis of Rts1p, a B' regulatory subunit of Saccharomyces cerevisiae protein phosphatase 2A