0B68 Covarrubias, Manuel L. - Thomas Jefferson University - Thomas Jefferson University

Manuel L. Covarrubias, MD, PhD

Contact Dr. Covarrubias

900 Walnut Street
Philadelphia, PA 19107

(215) 503-4241

Most Recent Peer-reviewed Publications

  1. Azi-isoflurane, a photolabel analog of the commonly used inhaled general anesthetic isoflurane
  2. Inhalational anaesthetics and n-alcohols share a site of action in the neuronal Shaw2 K v channel: Research paper
  3. A novel N-terminal motif of dipeptidyl peptidase-like proteins produces rapid inactivation of KV4.2 channels by a pore-blocking mechanism
  4. Kv4 channels underlie the subthreshold-operating A-type K+-current in nociceptive dorsal root ganglion neurons
  5. The dipeptidyl-peptidase-like protein DPP6 determines the unitary conductance of neuronal Kv4.2 channels
  6. The dipeptidyl-aminopeptidase-like protein 6 is an integral voltage sensor-interacting β-subunit of neuronal KV4.2 channels
  7. The neuronal Kv4 channel complex
  8. NMR analysis of KChIP4a reveals structural basis for control of surface expression of Kv4 channel complexes
  9. Ternary Kv4.2 channels recapitulate voltage-dependent inactivation kinetics of A-type K+ channels in cerebellar granule neurons
  10. Gating charge immobilization in Kv4.2 channels: The basis of closed-state inactivation
  11. Mechanism of the modulation of Kv4:KChIP-1 channels by external K
  12. Cumulative activation of voltage-dependent KVS-1 potassium channels
  13. Zn2+-dependent redox switch in the intracellular T1-T1 interface of a Kv channel
  14. A dipeptidyl aminopeptidase-like protein remodels gating charge dynamics in Kv4.2 channels
  15. The concerted contribution of the S4-S5 linker and the S6 segment to the modulation of a Kv channel by 1-alkanols
  16. Mutant analysis of the Shal (Kv4) voltage-gated fast transient K + channel in Caenorhabditis elegans
  17. Voltage-dependent gating rearrangements in the intracellular T1-T1 interface of a K+ channel
  18. Functionally active T1-T1 interfaces revealed by the accessibility of intracellular thiolate groups in Kv4 channels