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Current Studies

The Mood Disorders Program is actively seeking participants for the following three studies. 

  1. Sexual dysfunction study: The Mood Disorders Program at Thomas Jefferson University is leading a multicenter clinical trial for patients whose major depressive disorder has remitted with an antidepressant but who have antidepressant-related sexual dysfunction. Patients will be randomized to receive either vilazodone (Viibryd) or sertraline (Zoloft). No patient will receive only placebo. The study will last for up to 11 weeks. Participants will be reimbursed for their time and for travel.
  2. Genetic testing study: Patients who have taken or are currently taking certain antidepressant medications who EITHER
    1. Took the antidepressant and experienced significant side effects, OR 
    2. Took the antidepressant, had less than a 30% reduction in depression, and had minimal side effects. 
    Patients with qualifying health insurance will receive the Genecept assay to determine gene status of certain CYP 450 enzymes. This is only a two-visit study and results will be provided. There is no treatment in this study but the study psychiatrist will be available to discuss the results and treatment implications. Participants will be reimbursed for their time and for travel.
  3. Excessive Sweating study: Patients with clinical depression who have complaints of excessive sweating thought to be a side effect of their antidepressant may be suitable for participation in an ongoing clinical trial in which participants will have another medication added to an antidepressant to assess how well this potential drug works to treat sweating caused by antidepressants.  All patients will receive the medication; no placebo is used. 

For more information, please call (215) 503-2834

Depression Treatment Non-medication Study 
A unique 8-week research study at Thomas Jefferson University and the Myrna Brind Center of Intergrative Medicine is evaluating a nutritional supplement that may help relieve depression symptoms.  Enrolled participants will receive an initial evaluation, study nutritional supplement, and follow-up visits at no cost.  For more information call (215) 503-7469

In the News

Please join us for the 3rd Annual Sleep Medicine Symposium: “What’s New Under the Moon” on Friday, November 14, 2014 at the Dorrance H. Hamilton Building on the campus of Thomas Jefferson University.   For more information, please visit: http://jeffline.jefferson
.edu/ jeffcme/
or call the Office of CME at 1-888-JEFF-CME or (215) 955-6992.

to Drs. Salman Akhtar, Mitchell Cohen, Karl Doghramji, Elisabeth Kunkel, and Barry Rovner for making the Top Doctors Issue of Phila Magazine

Salman Akhtar, MD, Professor of Psychiatry at Thomas Jefferson University has edited a groundbreaking new book called The African American Experience: Psychoanalytic Perspectives.

Philadelphia Magazine

Taste of Mindfulness Class
November 11, 2014
12:00 - 1:00 p.m.
Open to TJU Students and TJUH House Staff
To register or for more information, visit

Special CME Grand Rounds on "Stroke and Sleep" by Dr. Antonio Culebras 
November 14, 2014 8:00 - 9:00 a.m.
Connelly Auditorium, Hamilton Building. No Registration requiered.

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