Paul Stauffer, MSEE, CCE
Room G-302A, Bodine Center
Philadelphia, PA 19107
Most Recent Peer-reviewed Publications
- Salvage brachytherapy in combination with interstitial hyperthermia for locally recurrent prostate carcinoma following external beam radiation therapy: A prospective phase II study
- Hyperthermia, radiation and chemotherapy: The role of heat in multidisciplinary cancer care
- Simulation techniques in hyperthermia treatment planning
- Thermal modelling using discrete vasculature for thermal therapy: A review
- The impact of temperature and urinary constituents on urine viscosity and its relevance to bladder hyperthermia treatment
College of Wooster, Wooster OH BA (Physics)
University of Arizona, Tucson AZ MSEE (Electrical Engineering, Clinical Engineering)
University of Arizona, Tucson AZ
Clinical Engineering, International Certification Commission (AAMI) 1983
Medical Physics with Specialization in Hyperthermia, American Board of Medical Physics (ABMP) 1991
Professor, Department of Radiation Oncology (2013)
Director of Thermal Oncology Physics (2013)
Research and Clinical Interests
I am an international authority in Hyperthermia treatment for cancer, including development and clinical implementation of novel methods for heating tumors and measuring temperature in the body. I am Past President of the Society for Thermal Medicine (STM), and have received the Eugene Robinson Award from STM and the Sugahara Oration Award from the Indian Association of Hyperthermia Oncology and Medicine for my work in advancing the field of thermal medicine.
I direct the Thermal Oncology Physics laboratory in the Radiation Oncology Department of the Kimmel Cancer Center at Thomas Jefferson University where we work on translation of heat treatment approaches from theoretical and experimental design engineering to laboratory testing and clinical use. I have been Principal Investigator of 16 NIH grant awards and 19 corporate contracts and grants. In conjunction with over 50 graduate students and post-doctoral research fellows, my laboratory has developed many new approaches to heating tissue and monitoring tissue temperature, for tumors close to the skin surface and at depth in the body. I have 9 US Patents on a range of developments including use of ultrasound to enhance drug delivery, miniature implantable microwave antennas for interstitial heat therapy, large area microwave vest for simultaneous delivery of heat and radiation, and non-invasive thermal monitoring arrays.
My interest in medical physics support of clinical Hyperthermia has led to the introduction of several new clinical techniques for improved treatment of cancer by combining heat with radiation, chemotherapy, and heat-targeted liposome and nanoparticle-delivered therapy. I have taken a leadership role in several workshops on Quality Assurance of Hyperthermia with RTOG, AAPM, and STM organizations, and have authored numerous publications on Quality Assurance. Recent research activity includes development of non-invasive thermal monitoring with multifrequency microwave radiometry for new diagnostic and therapeutic applications, and magnetic resonance thermal imaging for 3D volumetric dosimetry and treatment control.
I have published more than 130 peer-reviewed journal articles and book chapters and over 60 extended length proceedings articles and reports. I have served on the Editorial Boards of the International Journal of Radiation Oncology Biology and Physics, Medical Physics, and the International Journal of Hyperthermia, and provide reviews regularly for 10 scientific journals and grant agencies like NIH, NCI, Dutch Cancer Society, CDMRP, NCIC, and CRDF.