Contact Dr. Yu

111 South 11th Street
Room G-321, Bodine Center
Philadelphia, PA 19107

(215) 955-8855
(215) 955-0412 fax


Thomas Jefferson University, Philadelphia, Pennsylvania

Board Certification

Radiation Therapy Physics, American Board of Medical Physics, 1996


University of London, Queen Mary College, London, England, B.Sc. (Physics)
University of London, University College, London, England, Ph.D. (Atomic Molecular Physics)
Simon Business School, University of Rochester, Rochester, NY, M.B.A. (Business Administration)

University Appointment

Professor and Vice Chair
Director of Medical Physics Division, Department of Radiation Oncology, Thomas Jefferson University, 2008

Research and Clinical Interests

  • Stereotactic and IMRT treatment optimization using computational intelligence techniques. Decision analysis for radiotherapy planning.
  • Real-time error predictive treatment guidance. Time series analysis and forecasting. Optical interferometry-based prospective respiratory gating. Image-guided therapy and intervention.
  • Robotic assisted platform for radiation delivery, motion tracking.
  • Electromagnetic and optical tracking systems for therapy guidance and verification. Force sensory feedback control. Physiodynamic sensing.
  • Intraoperative dynamic dosimetry for prostate brachytherapy.
  • Optimization of needle-based, Image-guided intervention, including biopsy and therapy.
  • NIR functional imaging and spectroscopy of acoustic radiation force mediated vascular effects for non-invasive cancer detection and therapeutic intervention. Multimodal optical imaging for cancer detection, disease mapping and IGT.
  • High intensity focused ultrasound for ablative therapy.
  • 3D orthogonal compound ultrasound.
  • Image analysis, pattern recognition and image fusion.
  • Plasma atomic physics and electron beam ion trap fluorescent radiation, theory and instrumentation.
  • Animal models of tissue oxygenation, tumor vasculature and normalization. Vascular disruptive agents using nanoparticle-enhanced radiation.
  • Microbeam RT: from cells to small animals.