Thomas Jefferson UniversitySidney Kimmel Medical College

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Current Research Programs

Research activities are conducted by 12 faculty radiologists, 7 fellows, 2 physicists and support staff including 3 research sonographers, several nurses and research coordinators.

Basic Research

The department of radiology and the Institute conduct a broad spectrum of research collaboration with our affiliate institutions. In addition to faculty-conducted research by members of Jefferson's ultrasound team and our affiliates, graduate students from Drexel University participate in research studies under the guidance of the department's physicists and Drexel faculty who have adjunct appointments at Jefferson.

Current ongoing research projects in the basic sciences area include:

  • Developing novel techniques for noninvasive quantization of blood flow
  • Investigating the behavior of ultrasound contrast agents
  • Assessing the biological effects of ultrasound contrast agents
  • Analyzing ultrasound tissue signatures for tumor characterization
  • Computer reconstruction of Doppler flow maps of tissue perfusion
  • Developing improved three-dimensional ultrasound imaging

Clinical Research

Basic research activities are complemented by an extensive program of clinical research. The primary emphasis of this clinical research is to increase our knowledge and expand the uses of diagnostic ultrasound in the patient care setting. Results of the various research projects are reported each year in peer-reviewed journals. The staff also shares our research findings with a broader global audience, delivering lectures and presentations throughout the world.

A few of the current clinical research projects include:

  • Developing improved Doppler ultrasound measurement techniques in pregnancy
  • Using two-dimensional ultrasound to detect fetal defects
  • Using miniature transducers for endoluminal studies in a variety of hollow organs and surgically created openings
  • Using color Doppler in early detection of ovarian, endometrial, breast, rectal and prostate cancers
  • Evaluating ultrasound guided needles to increase the accuracy of ultrasound aspiration and biopsy techniques
  • Use of ultrasound contrast agents in evaluating venous thrombi, improving visualization of arterial abnormalities and detecting tumors in the early stages of their development
  • Evaluating new techniques for more accurate noninvasive measurement of blood flow