3908 Bhushan, Alok - Thomas Jefferson University
Thomas Jefferson University

Bhushan, Alok

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Alok Bhushan, PhD

Contact Dr. Bhushan

901 Walnut Street
9th Floor, Suite 915
Philadelphia, PA 19107

(215) 503-5039
(215) 503-3082 fax

Undergraduate School:

BS (Hons) Chemistry, University of Delhi, India, 1975

Graduate School:

MS Chemistry, University of Delhi, India, 1977
PhD, Punjab Agricultural University, India, 1982

Postgraduate Training:

Johns Hopkins College of Medicine, Baltimore, MD:
Postdoctoral Fellow, 1983-1984;
Medical University of South Carolina, Department of Pediatrics, Charleston, SC:
Postdoctoral Fellow, 1984-1987;
University of Vermont, Department of Pharmacology, Burlington, VT:
Postdoctoral Fellow, 1987-1988

Professional Organizations

American Association of Cancer Research
American Association of College of Pharmacy
American Society of Biochemistry and Molecular Biology
American Association for Advancement of Science
Sigma Xi Scientific Society

Research/Clinical Interests:

Cancer Pharmacology and Signal Transduction focused on Treatment and Prevention



Most Recent Peer-Reviewed Publications

  1. Biochanin A inhibits endothelial cell functions and proangiogenic pathways: Implications in glioma therapy
  2. Tyrosine phosphorylation of HSC70 and its interaction with RFC mediates methotrexate resistance in murine L1210 leukemia cells
  3. Biochanin A reduces pancreatic cancer survival and progression
  4. Cytotoxic effects of silver and gold nanoparticles in human glioblastoma U87 cells
  5. Zinc oxide nanoparticles induced apoptosis and necrosis in human neuroblastoma and astrocytoma cells
  6. Interleukin-6 and JAK2/STAT3 signaling mediate the reversion of dexamethasone resistance after dexamethasone withdrawal in 7TD1 multiple myeloma cells
  7. Zinc oxide nanoparticles induce apoptosis and necrosis in hepatocellular carcinoma HepG2 cells
  8. Entry of short multi-wall carbon nanotubes into dorsal root ganglion (DRG) neurons induces cell death
  9. Identification and characterization of a 66-68-kDa protein as a methotrexate-binding protein in murine leukemia L1210 cells
  10. Cytotoxic effects of four metallic oxide nanoparticles on dorsal root g 2238 anglion (DRG) neurons
  11. Cytotoxicity of magnesium oxide nanoparticles in Schwann cells
  12. Cytotoxic effects of short multi-wall carbon nanotubes in dorsal root ganglion (DRG) neurons
  13. Effects of silicon dioxide nanoparticles on peripheral nervous system neural cell models
  14. Molecular effects of silicon dioxide nanoparticles on cell survival signaling of Dorsal Root Ganglion (DRG) neurons and schwann cells
  15. New in vitro strategy of astrocytoma (astrocytes-like) cells treated with pioglitazone (PPAR gamma agonist) offers neuroprotection against nanoparticles-induced cytotoxicity
  16. Differential cytotoxic effects of titanium oxide nanoparticles on peripheral nervous system neural cells
  17. Treatment of human astrocytoma U87 cells with silicon dioxide nanoparticles lowers their survival and alters their expression of mitochondrial and cell signaling proteins
  18. Bioactive isoflavones: Implications in cancer treatment and prevention
  19. Elucidation of neuroprotective properties of astrocytoma (astrocytes-like) cells in neural cell culture models in vitro: Applications in tissue engineering and nanotoxicology
  20. A noncontact co-culture model of peripheral neural cells for nanotoxicity, tissue engineering and pathophysiological studies