Philadelphia University + Thomas Jefferson University

Winter Laboratory

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Description

We study basic, translational, and clinical aspects of pancreatic cancer with a principle goal to discover new and effective therapies. Our research program uses and integrates several different model systems for our research investigations, including tissue culture models derived from the patients we treat, commercial cell lines, mouse models of pancreatic cancer, and a clinical database with a complementary biologic tissue repository. With these resources, we are trying to develop innovative strategies to personalize therapy and to understand how pancreatic cancers develop resistance to standard chemotherapies. Additionally, we are interested in understanding how pancreatic cancer is able to successfully adapt to the extremely harsh metabolic conditions that are present throughout the tumor microenvironment such as hypoxia and low nutrient levels. Our aim is to design therapies that specifically target these adaptive mechanisms.

 

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Jordan Winter, MD
Associate Professor

Contact Dr. Winter

1025 Walnut Street
College Building, Suite 611
Philadelphia, PA 19107

(215) 955-1171