Thomas Jefferson University
Sidney Kimmel Medical College
Department of Medicine

Research Activity

Our strong clinical research program, especially in the fields of acute kidney injury and hypertension, has been complemented by our growing basic research program in regulation of ion transport. We have obtained extramural funding for a broad range of clinical research projects in the areas of diabetic nephropathy, dialysis, nutrition and renal transplantation. Our NIH funded basic science research is focused on hypertension and regulation of ion transplant by FXYD proteins.

Bonita Falkner, M.D., Director of Hypertension

Research interests include the genetic basis of essential hypertension, insulin resistance and obesity.

Representative Publications

Treatment-induced changes in plasma adiponectin do not reduce urinary albumin excretion in the diabetes prevention program cohort

Right analysis-wrong conclusion: Obese youth with higher BP are at risk for target organ damage

Recent clinical and translational advances in pediatric hypertension

Adolescent and adult African Americans have similar metabolic dyslipidemia

Cardiometabolic risks related to obesity severity in children and adolescents: A commentary

Is there a bend in the upward trend of high blood pressure in childhood? A commentary on prevalence of and trends in dyslipidemia and blood pressure among US children and adolescents, 1999-2012

Associations of cardiac structure with obesity, blood pressure, inflammation, and insulin resistance in african-american adolescents

Response to "U.S. Preventive Services Task Force Recommendation and Pediatric Hypertension Screening: Dereliction of Duty or Call to Arms?"

Understanding the power of perinatal events and metabolic status in childhood

Fibroblast growth factor-23 in obese, normotensive adolescents is associated with adverse cardiac structure

Prevalence of metabolic syndrome and obesity-associated hypertension in the racial ethnic minorities of the United States

Obesity associated inflammation in African American adolescents and adults

A double-blind randomized trial of fish oil to lower triglycerides and improve cardiometabolic risk in adolescents

Response to hypertension and children: Should we be aware?

Effects of a web-based patient activation intervention to overcome clinical inertia on blood pressure control: Cluster randomized controlled trial

What childhood blood pressure studies reveal about genetics and environment

Childhood blood pressure trends and risk factors for high blood pressure: The NHANES experience 1988-2008

Non-invasive assessment of microvascular and endothelial function.

The adipose tissue production of adiponectin is increased in end-stage renal disease

A Genome-Wide Methylation Study on Essential Hypertension in Young African American Males

Maria P. Martinez Cantarin, M.D.

Research interests include Adipose tissue inflammation, kidney disease and transplant associated hyperglycemia.  

Representative Publications

Pooja Singh, M.D.

Research interests include immunological barriers in renal transplantation, sensitization and renal allograft failure management.

Representative Publications

Recent Peer Reviewed Publications by Division

Sensitization trends after renal allograft failure: The role of DQ eplet mismatches in becoming highly sensitized

Need to consider full societal impact of hepatitis B virus-positive donors

Treatment-induced changes in plasma adiponectin do not reduce urinary albumin excretion in the diabetes prevention program cohort

Right analysis-wrong conclusion: Obese youth with higher BP are at risk for target organ damage

Recent clinical and translational advances in pediatric hypertension

Adolescent and adult African Americans have similar metabolic dyslipidemia

Cardiometabolic risks related to obesity severity in children and adolescents: A commentary

Is there a bend in the upward trend of high blood pressure in childhood? A commentary on prevalence of and trends in dyslipidemia and blood pressure among US children and adolescents, 1999-2012

Association of SOCS3 gene polymorphisms with insulin resistance in Xinjiang Uygur population

Relationship between female dyslipidemia and polymorphism of suppressor of cytokine signaling-3 in Xinjiang Uygur population

Associations of cardiac structure with obesity, blood pressure, inflammation, and insulin resistance in african-american adolescents

Association of glucose transporter 4 genetic Polymorphisms with obstructive sleep apnea syndrome in Han Chinese general population: A cross-section study

Response to "U.S. Preventive Services Task Force Recommendation and Pediatric Hypertension Screening: Dereliction of Duty or Call to Arms?"

Understanding the power of perinatal events and metabolic status in childhood

Fibroblast growth factor-23 in obese, normotensive adolescents is associated with adverse cardiac structure

Prevalence of metabolic syndrome and obesity-associated hypertension in the racial ethnic minorities of the United States

Quantifying the risk of incompatible kidney transplantation: A multicenter study

Obesity associated inflammation in African American adolescents and adults

A double-blind randomized trial of fish oil to lower triglycerides and improve cardiometabolic risk in adolescents

Sensitization, pathologic, and imaging findings comparing symptomatic and quiescent failed renal allografts