Thomas Jefferson University
Sidney Kimmel Medical College
Department of Medicine

Ma, Xin-Liang

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Xin-Liang Ma

Xin-Liang Ma, MD

Contact Dr. Ma

1025 Walnut Street
Suite 808
Philadelphia, PA 19107

(215) 955-4994
(215) 503-4458 fax

Medical School

The Fourth Military Medical University, China


Thomas Jefferson University

University Appointment

Professor of Emergency Medicine,
Professor of Medicine

Research & Clinical Interests

Protection of Myocardial Injury (ischemia. Reperfusion, diabetes)


Most Recent Peer-Reviewed Publications

  1. Hyperglycemia abrogates ischemic postconditioning cardioprotection by impairing AdipoR1/Caveolin-3/STAT3 signaling in diabetic rats
  2. Adiponectin at physiologically relevant concentrations enhances the vasorelaxative effect of acetylcholine via Cav-1/AdipoR-1 signaling
  3. Plasma IgG antibody against cytomegalovirus but not herpes simplex virus is associated with recurrence of atrial fibrillation after catheter ablation
  4. Cloning and transcriptional activity of the mouse Omi/HtrA2 gene promoter
  5. Reduction of CTRP9, a novel anti-platelet adipokine, contributes to abnormal platelet activity in diabetic animals
  6. Preparation and biological activity of the monoclonal antibody against the second extracellular loop of the angiotensin II type 1 receptor
  7. PPARγ Agonist Ameliorates the Impaired Fluidity of the Myocardial Cell Membrane and Cardiac Injury in Hypercholesterolemic Rats
  8. High glucose/High Lipids impair vascular adiponectin function via inhibition of caveolin-1/AdipoR1 signalsome formation
  9. Irisin improves endothelial function in type 2 diabetes through reducing oxidative/nitrative stresses
  10. Pro-arrhythmic action of autoantibodies against the second extracellular loop of β<inf>1</inf>-adrenoceptor and its underlying molecular mechanisms
  11. Trans-system mechanisms against ischemic myocardial injury
  12. C1q-TNF-related protein-9, a novel cardioprotetcive cardiokine, requires proteolytic cleavage to generate a biologically active globular domain isoform
  13. G-protein-coupled receptor kinase 2-mediated desensitization of adiponectin receptor 1 in failing heart
  14. Activation of κ-opioid receptor exerts the glucose-homeostatic effect in streptozotocin-induced diabetic mice
  15. AdipoRon, the first orally active adiponectin receptor activator, attenuates postischemic myocardial apoptosis through both AMPK-mediated and AMPK-independent signalings
  16. Angiotensin II type 1 receptor autoantibody as a novel regulator of aldosterone independent of preeclampsia
  17. Concomitant retrograde coronary venous infusion of basic fibroblast growth factor enhances engraftment and differentiation of bone marrow mesenchymal stem cells for cardiac repair after myocardial infarction
  18. Effective glycaemic control critically determines insulin cardioprotection against ischaemia/reperfusion injury in anaesthetized dogs
  19. Erratum: Long-term active immunization with a synthetic peptide corresponding to the second extracellular loop of β1-adrenoceptor induces both morphological and functional cardiomyopathic changes in rats (International Journal of Cardiology (2011) 149:1 (89-94))
  20. Adiponectin inhibits tumor necrosis factor-α-induced vascular inflammatory response via caveolin-mediated ceramidase recruitment and activation