Philadelphia University + Thomas Jefferson University
Sidney Kimmel Medical College
Department of Medicine

Ma, Xin-Liang

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Xin-Liang Ma

Xin-Liang Ma, MD

Contact Dr. Ma

1025 Walnut Street
Suite 808
Philadelphia, PA 19107

(215) 955-4994
(215) 503-4458 fax

Medical School

The Fourth Military Medical University, China

Fellowship

Thomas Jefferson University

University Appointment

Professor of Emergency Medicine,
Professor of Medicine

Research & Clinical Interests

Protection of Myocardial Injury (ischemia. Reperfusion, diabetes)

Publications

Most Recent Peer-Reviewed Publications

  1. Mitochondrial Omi/HtrA2 Promotes Caspase Activation Through Cleavage of HAX-1 in Aging Heart
  2. T-cadherin deficiency increases vascular vulnerability in T2DM through impaired NO bioactivity
  3. Role of adipokines in cardiovascular disease
  4. PPARγ Agonist Ameliorates the Impaired Fluidity of the Myocardial Cell Membrane and Cardiac Injury in Hypercholesterolemic Rats
  5. Cardiac Specific Overexpression of Mitochondrial Omi/HtrA2 Induces Myocardial Apoptosis and Cardiac Dysfunction
  6. Branched Chain Amino Acids Cause Liver Injury in Obese/Diabetic Mice by Promoting Adipocyte Lipolysis and Inhibiting Hepatic Autophagy
  7. Hyperglycemia abrogates ischemic postconditioning cardioprotection by impairing AdipoR1/Caveolin-3/STAT3 signaling in diabetic rats
  8. Adiponectin at physiologically relevant concentrations enhances the vasorelaxative effect of acetylcholine via Cav-1/AdipoR-1 signaling
  9. Plasma IgG antibody against cytomegalovirus but not herpes simplex virus is associated with recurrence of atrial fibrillation after catheter ablation
  10. Cloning and transcriptional activity of the mouse Omi/HtrA2 gene promoter
  11. Reduction of CTRP9, a novel anti-platelet adipokine, contributes to abnormal platelet activity in diabetic animals
  12. Preparation and biological activity of the monoclonal antibody against the second extracellular loop of the angiotensin II type 1 receptor
  13. High glucose/High Lipids impair vascular adiponectin function via inhibition of caveolin-1/AdipoR1 signalsome formation
  14. Irisin improves endothelial function in type 2 diabetes through reducing oxidative/nitrative stresses
  15. Pro-arrhythmic action of autoantibodies against the second extracellular loop of β<inf>1</inf>-adrenoceptor and its underlying molecular mechanisms
  16. Trans-system mechanisms against ischemic myocardial injury
  17. G-protein-coupled receptor kinase 2-mediated desensitization of adiponectin receptor 1 in failing heart
  18. C1q-TNF-related protein-9, a novel cardioprotetcive cardiokine, requires proteolytic cleavage to generate a biologically active globular domain isoform
  19. Concomitant retrograde coronary venous infusion of basic fibroblast growth factor enhances engraftment and differentiation of bone marrow mesenchymal stem cells for cardiac repair after myocardial infarction
  20. Activation of κ-opioid receptor exerts the glucose-homeostatic effect in streptozotocin-induced diabetic mice